| Agent Name |
sec-Amyl acetate |
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| Alternative Name |
1-Methylbutyl acetate, 2-Pentyl acetate |
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| CAS Number |
626-38-0 |
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| Formula |
C7-H14-O2 |
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| Major Category |
Solvents |
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| Synonyms |
1-Methylbutyl acetate; 2-Acetoxypentane; 2-Amylester kyseliny octove [Czech]; 2-Pentanol, acetate; 2-Pentyl acetate; sec-Amyl acetate; sek.Amylester kyseliny octove [Czech]; [ChemIDplus] |
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| Category |
Esters |
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| Description |
Colorless liquid with a mild odor; [NIOSH] |
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| Sources/Uses |
Used as a solvent for ethyl cellulose, nitrocellulose, printing inks; also used in the production of coatings and cements; [ACGIH] |
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| Comments |
Esters may induce narcosis in animals, but workers' exposures are limited by irritating effects. See appendix in: [Dick RB, et al. Chemicals in the workplace: incorporating human neurobehavioral testing into the regulatory process. Am J Ind Med. 1998 May;33(5):439-53.] |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
No |
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| TLV (ACGIH) |
50 ppm |
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| STEL (ACGIH) |
100 ppm |
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| PEL (OSHA) |
125 ppm |
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| MAK |
50 ppm |
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| IDLH (NIOSH) |
1000 ppm |
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| Excerpts from Documentation for IDLHs |
The chosen IDLH is based on the statement by Browning [1965] that exposure to 4,000 ppm of a mixture of n-amyl acetate and isoamyl acetate produced complete loss of reflexes in rabbits within an hour [Koelsch 1912], and on the statement by Sax [1975] that 5,000 ppm n-amyl acetate produced deep narcosis in cats in 30 minutes. |
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| Vapor Pressure |
9.78 mm Hg |
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| Odor Threshold Low |
0.002 ppm |
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| Odor Threshold High |
0.08 ppm |
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| Explanatory Notes |
Odor threshold from CHEMINFO; Flash point = 32 deg C; |
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| Half Life |
No reports found; [TDR, p. 95] |
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| Flammability (NFPA) |
3: may ignite at ambient temperature |
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| Adverse Effects |
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| Neurotoxin |
CNS Solvent Syndrome |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: 2-PENTYL ACETATE
|
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