Agent Name |
Toluene 2,6-diisocyanate |
CAS Number |
91-08-7, 26471-62-5 |
Formula |
C9-H6-N2-O2 |
Major Category |
Plastics & Rubber |
Synonyms |
1,3-Diisocyanato-2-methylbenzene; 2,6-Diisocyanato-1-methylbenzene; 2,6-Diisocyanatotoluene; 2,6-TDI; 2-Methyl-meta-phenylene isocyanate; Benzene, 1,3-diisocyanato-2-methyl-; Benzene, 2,6-diisocyanato-1-methyl-; Isocyanic acid, 2-methyl-meta-phenylene ester; 2,6-Toluene diisocyanate; Tolylene 2,6-diisocyanate; UN 2078; m-Tolylene diisocyanate; meta-Tolylene diisocyanates; [ChemIDplus] |
Category |
Diisocyanates |
Description |
Colorless to pale-yellow liquid with a sharp, acrid odor; [ACGIH] |
Sources/Uses |
Occupational asthma reported in floor varnishers and in workers manufacturing polyurethane foams and elastomers; [Malo] |
Comments |
"Most reports on TDI failed to specify which isomer was studied or to define its purity; . . . No important toxicologic distinctions between the 2,4- and 2,6-isomers are recognized." [ACGIH] See "2,4-Toluene diisocyanate." |
Reference Link |
Occupational asthma due to isocyanates |
Exposure Assessment |
Skin Designation (ACGIH) |
No |
TLV (ACGIH) |
0.005 ppm |
STEL (ACGIH) |
0.02 ppm |
Vapor Pressure |
0.02 mm Hg |
Explanatory Notes |
See 2008 Notice of Intended Changes. [ACGIH] |
Reference Link |
ATSDR Medical Management -Toluene diisocyanate |
Adverse Effects |
Asthma |
Yes |
Toxic Pneumonitis |
Yes |
Fibrogenic |
Yes |
Dermatotoxin |
Skin Burns |
Skin Sensitizer |
Yes |
Lacrimator |
Yes |
IARC Carcinogen |
Possible Carcinogen |
Links to Other NLM Databases |
Health Studies |
Human Health Effects from Hazardous Substances Data Bank: 2,6-TOLUENE DIISOCYANATE
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