Cancer Control Research
5R13CA095124-03
Green, Daniel M.
LONG-TERM COMPLICATIONS OF CHILDREN/ADOLESCENTS & CANCER
Abstract
DESCRIPTION (provided by applicant):
We propose to hold a two-day conference on June 28-29, 2002 at Queen's Landing
Inn (Niagara-on-the-Lake, Ontario, Canada). The program will be of interest
to pediatric hematologists/oncologists, pediatric nurse practitioners,
pediatric psychologists, pediatric oncology social workers, medical
oncologists, fellows, residents, interns, clinical research associates and
other primary care providers. The topic of bone complications following
treatment of children and adolescents for cancer will be addressed.
The goals of the 7th International Conference on Long-Term Complications of
Treatment of Children and Adolescents for Cancer will be to: 1) Review the
biology of the basic multicellular unit; 2) review the role of the kidney in
the regulation of calcium metabolism; 3) review the effect of cis-platinum on
renal function and calcium metabolism; 4) review the late effects of
ifosfamide on the kidney; 5) review the issues involved in the measurement of
bone density; 6) review the effects of radiation therapy effects on bone
density; 7) review the effects of glucocorticoid hormones on bone density; 8)
review the roles of androgen and estrogen in skeletal physiology; 9) review
the issues involved in the management of osteoporosis due to ovarian failure;
10) review the role of growth hormone in the regulation of bone density; and
11) review the issues involved in the duration of treatment with growth
hormone replacement therapy.
The conference will include presentations by nationally and internationally
recognized experts in these areas. The conference will facilitate subsequent
discussions among the investigators of the Childhood Cancer Survivor Study,
most of whom attend this conference, regarding future research on bone
complications among participants in the Childhood Cancer Survivor Study.
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