| Agent Name |
4-Aminophenol |
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| Alternative Name |
p-Aminophenol |
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| CAS Number |
123-30-8 |
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| Formula |
C6-H7-N-O |
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| Major Category |
Nitrogen Compounds |
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| Synonyms |
1-Amino-4-hydroxybenzene; 4-Amino-1-hydroxybenzene; 4-Aminophenol; 4-Hydroxyaniline; Activol; Azol; BASF Ursol P Base; Benzofur P; C.I. 76550; C.I. Oxidation Base 6; CI 76550; Certinal; Citol; Durafur Brown RB; Fouramine P; Fourrine 84; Fourrine P Base; Furro P Base; Nako Brown R; PAP; Paranol; Pelagol Grey P Base; Pelagol P Base; Renal AC; Rodinal; Tertral P base; Unal; Ursol P; Ursol P base; Zoba Brown P Base; p-Aminofenol [Czech]; p-Aminophenol; p-Hydroxyaniline; p-Hydroxyphenylamine; [ChemIDplus] UN2512 |
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| Category |
Amines, Aromatic |
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| Description |
White or reddish-yellow crystals or light-brown powder that turns violet when exposed to light; [CAMEO] |
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| Sources/Uses |
Used as a dye for textiles, hair, furs, and feathers; also used as a photographic developer and chemical intermediate for pharmaceuticals and dyes; [HSDB] |
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| Comments |
The lethal oral dose in humans is in the range of 50-500 mg/kg. p-Aminiophenol induces methemoglobinemia in experimental animals, but it is not as potent as aniline. It is a potential sensitizer of the skin and respiratory tract. [HSDB] "Symptoms of exposure to this chemical may include asthma, irritation of the skin and eyes, dermatitis and methemoglobinemia with cyanosis; This compound is a skin and eye irritant and an allergen." [CAMEO] |
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| Reference Link |
Occupational allergic contact dermatitis in beauticians |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
Not evaluated |
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| Vapor Pressure |
4 x 10 -05 mm Hg |
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| Lethal Concentration |
LC50 (rats) =>5 mg/m3/1H |
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| Explanatory Notes |
Melting point = 367-369 degrees F; [CAMEO] |
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| Adverse Effects |
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| Asthma |
Yes |
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| Methemoglobinemia |
Methemoglobinemia, Secondary |
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| Skin Sensitizer |
Yes |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: 4-AMINOPHENOL
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