| Agent Name |
Trimethyl phosphite |
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| CAS Number |
121-45-9 |
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| Formula |
C3-H9-O3-P |
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| Major Category |
Other Classes |
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| Synonyms |
Fosforyn trojmetylowy [Czech]; Trimethoxyfosfin [Czech]; Trimethoxyphosphine; Trimethyl phosphite; Trimethylfosfit [Czech]; [ChemIDplus] UN2329 |
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| Category |
Phosphorus Compounds |
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| Description |
Colorless liquid with a distinctive, pungent odor; [NIOSH] |
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| Sources/Uses |
Used in the manufacture of pesticides, flame-retardant textiles, and polyurethane foams; also used as a catalyst; [ACGIH] |
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| Comments |
Corrosive to skin; [Quick CPC] Liquid causes second or third degree burns after short contact. [CHRIS] Dose dependent cataract formation occurs in rats exposed to concentrations above 100 ppm. Lung inflammation occurs in animals exposed at 600 ppm. Human subjects complain of objectionable odor above 20 ppm. No adverse health effects were found in 179 employees exposed regularly to 0.3 to 8 ppm. [ACGIH] A severe skin, eye, and respiratory tract irritant; [ICSC] |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
No |
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| TLV (ACGIH) |
2 ppm |
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| Vapor Pressure |
18.7 mm Hg |
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| Odor Threshold Low |
0.001 ppm |
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| Lethal Concentration |
LCLo (rats) = 32,700 mg/m3/6h |
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| Explanatory Notes |
Odor threshold from AIHA; Flash pint = 54 deg C; |
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| Flammability (NFPA) |
3: may ignite at ambient temperature |
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| Adverse Effects |
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| Toxic Pneumonitis |
Yes |
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| Dermatotoxin |
Skin Burns |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: TRIMETHYL PHOSPHITE
|
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