| Agent Name |
Tetrakis (hydroxymethyl) phosphonium salts |
|---|
| CAS Number |
124-64-1, 55566-30-8 |
|---|
| Formula |
C4-H12-O4-P.Cl; C8-H24-O8-P2.O4-S |
|---|
| Major Category |
Other Chemicals |
|---|
| Synonyms |
124-64-1: Phosphonium, tetrakis(hydroxymethyl)-, chloride; Pyroset TKC; Retardol C; THPC; Tetrahydroxymethylphosphonium chloride; Tetrakis(hydroxymethyl)phosphochloride; Tetrakis(hydroxymethyl)phosphonium chloride; Tetrakis-(hydroxymethyl)fosfoniumchlorid [Czech] ; Tetramethylolphosphonium chloride; 55566-30-8: Bis(tetrakis(hydroxymethyl)phosphonium)sulfate (salt); Octakis(hydroxymethyl)phosphonium sulfate; Phosphonium, tetrakis(hydroxymethyl)-, sulfate (2:1) (salt) ; Pyroset TKO; THPS; Tetrakis(hydroxymethyl)phosphonium sulfate; [ChemIDplus] |
|---|
| Category |
Phosphorus Compounds |
|---|
| Description |
Crystalline solid; [ACGIH] |
|---|
| Sources/Uses |
Used to make crease-resistant and flame-retardant finishes for textiles, e.g., children's sleepwear; [ACGIH] |
|---|
| Comments |
Reacts with water to form phosphine and formaldehyde; [CAMEO] Tetrakis (hydroxymethyl) phosphonium sulfate (THPS) was a sensitizer in 14 of 20 guinea pigs; Tetrakis (hydroxymethyl) phosphonium chloride (THPC) was not a skin sensitizer in tests on human skin; Neither THPS or THPC inhibited acetylcholinesterase; Rats and mice given repeated high oral doses have liver damage; [ACGIH] |
|---|
| Exposure Assessment |
|---|
| Skin Designation (ACGIH) |
No |
|---|
| TLV (ACGIH) |
2 mg/m3 |
|---|
| Explanatory Notes |
VP = 1 mm Hg @ 77 deg F (THPC); VP = 32 mm Hg @ 124 deg F (THPS); [CAMEO] |
|---|
| Adverse Effects |
|---|
| Skin Sensitizer |
Yes |
|---|
| Hepatotoxin |
Hepatotoxin, Secondary |
|---|
| IARC Carcinogen |
Not Classifiable |
|---|
| Links to Other NLM Databases |
|---|
| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: Tetrakis (hydroxymethyl) phosphonium salts
|
|---|
|
|
