| Agent Name |
Diglycidyl ether |
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| Alternative Name |
DGE |
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| CAS Number |
2238-07-5 |
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| Formula |
C6-H10-O3 |
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| Major Category |
Plastics & Rubber |
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| Synonyms |
1,2,6,7-Diepoxy-4-oxaheptane; Bis(2,3-epoxy-1 propyl) ether; Bis(2,3-epoxypropyl) ether; DGE; Di(2,3-epoxy)propyl ether; Diallyl Ether Dioxide; Diepoxy propyl ether; Diglycidyl ether; Ether, bis(2,3-epoxypropyl); Ether, diglycidyl; Glycidyl ether; [ChemIDplus] |
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| Category |
Glycidyl Ethers |
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| Description |
Colorless liquid with a strong, irritating odor; [NIOSH] |
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| Sources/Uses |
DGE is used in epoxy resins; it is also used to treat textiles and to stabilize chlorinated organic compounds. [ACGIH] |
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| Comments |
The TLV is based on male reproductive effects and irritation to the skin and eyes. Male rats develop reproductive toxicity after 60 4-hour exposures to 0.3 ppm. High concentrations induce CNS depression in experimental animals. In the past, some workers developed slow healing burns. [ACGIH] Severely irritating to the respiratory tract and may cause pulmonary edema; May cause skin sensitization; [ICSC] |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
No |
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| TLV (ACGIH) |
0.01 ppm |
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| PEL (OSHA) | Ceiling(OSHA) = 0.5 ppm |
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| IDLH (NIOSH) |
10 ppm |
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| Excerpts from Documentation for IDLHs |
Basis for original (SCP) IDLH: The chosen IDLH is based on the male mouse 4�hour LC50 of 30 ppm [Hine et al. 1956]. . . . Human data: None relevant for use in determining the revised IDLH. |
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| Vapor Pressure |
0.09 mm Hg |
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| Odor Threshold Low |
5 ppm |
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| Lethal Concentration |
LC50 (rats) = 200 ppm/4H |
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| Explanatory Notes |
An odor threshold has not been established, but DGE is recognizable by odor above 5 ppm; [ACGIH] Flash point = 64 deg C; |
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| Adverse Effects |
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| Toxic Pneumonitis |
Yes |
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| Dermatotoxin |
Skin Burns |
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| Skin Sensitizer |
Yes |
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| Reproductive Toxin |
Yes |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: DIGLYCIDYL ETHER
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