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DAIDS, DAIT, DMID

NIAID's divisions are particularly interested in applications that address the areas listed below. Also read NIAID's section of the Small Business Program Descriptions and Research Topics.

Division of AIDS -- Small Business High-Priority Areas of Interest

Updated April 29, 2008.

Areas of Interest Contact Email Phone
Preclinical development and evaluation of HIV vaccines, adjuvants, delivery systems, and novel technologies to enhance vaccine potency to prevent HIV infection or disease. Yen Li yli@niaid.nih.gov 301-496-3816
Development of anti-HIV agents directed at new viral or cellular targets. Paul Black pblack@niaid.nih.gov 301-496-2970
Development of novel anti-HIV drugs and therapeutics with focus on technological aspects such as multiplex analysis of drugs and better means of drug screening and drug delivery. Kailash Gupta kgupta@niaid.nih.gov 301-435-3724
Preclinical microbicide development of combination microbicides (multiple compounds, targets of activity against HIV and STIs associated with HIV acquisition); new chemical classes with specific mechanisms of action and antiviral targets, new microbicide targets, and formulation and delivery approaches for new and existing microbicides. Jim A. Turpin jturpin@niaid.nih.gov 301-451-2732
Development, standardization, validation, and evaluation of improved technologies to detect HIV, to evaluate immune responses to HIV vaccines, or to correlate immune responses associated with vaccine efficacy. Marco Schito schitom@niaid.nih.gov 301-594-5374
Development and evaluation of practical and affordable tests to measure viral load, CD4+ cell counts, and drug toxicities to monitor populations in resource-poor settings. Development of tests to detect early infection in seropositive HIV-infected individuals. Michael Ussery mussery@niaid.nih.gov 301-402-0134
Development of new therapeutic options for treatment of MDR-TB and XDR-TB in the setting of HIV infection and antiretroviral therapy. Development of rapid diagnostic tests for tuberculosis/HIV, TB drug resistance, and monitoring response to therapy. Chris Lambros

cl29r@nih.gov

301-435-3769
Preclinical discovery and development of antimicrobial agents directed against Mycobacterium avium, Pneumocystis pneumonia, and Cryptococcus neoformans (and other pathogenic fungi). Chris Lambros cl29r@nih.gov 301-435-3769
Preclinical development and evaluation of therapeutic vaccines and other immune-based therapies to attenuate HIV disease progression or reduce HIV infectiousness. Tony Conley conleyto@niaid.nih.gov 301-451-2739
Development of gene therapies for HIV. Frosso Voulgaropoulou frossov@mail.nih.gov 301-451-2704
Research to assess and overcome specific biomedical obstacles in HIV vaccine discovery, especially by application of novel technology to vaccine discovery or by the development and supply of novel reagents and other resources useful in novel vaccine discovery. Stuart Shapiro sshapiro@niaid.nih.gov 301-402-0122
Preclinical pre-exposure prophylaxis (PrEP) development (single or multiple agents, immunological, pharmacological, or other potential approaches directed against viral and/or host targets), including new classes of agents, examination of specific mechanisms of action and antiviral targets, new formulation procedures and delivery strategies for PrEP agents, optimization of animal models, and related research. David Burns burnsda@niaid.nih.gov 301-435-8896

Division of Allergy, Immunology, and Transplantation -- Small Business High-Priority Areas of Interest

Updated December 24, 2008.

Areas of Interest Contact Email Phone
Development of medical countermeasures to protect against, mitigate, and treat the short- and long-term effects of radiation exposure due to terrorist attack. Andrea DiCarlo-Cohen ad292x@nih.gov 301-451-9199
Development of novel or improved decorporation agents to remove radionuclides from the body following accidental inhalation, ingestion or wound entry. David Cassatt dc458x@nih.gov 301-451-3124
Identification of radiation exposure biomarkers and development of new biodosimetry methods and devices for triage of radiation-exposed people. Narayani Ramakrishnan nr57h@nih.gov 301-451-3101
Novel approaches for detecting infants at risk for developing asthma and other allergic diseases. Matthew Fenton fentonm@niaid.nih.gov 301-496-8973
Immune targets for asthma and allergic disease interventions. Development of immunotherapies to prevent or treat allergic diseases. Matthew Fenton fentonm@niaid.nih.gov 301-496-8973
Single cell assays to isolate and study allergen-specific lymphocytes. Matthew Fenton fentonm@niaid.nih.gov 301-496-8973
Development of new reagents and non-muting animal models for allergy research. Matthew Fenton fentonm@niaid.nih.gov 301-496-8973
Innovative treatments for autoimmune diseases. Josiah Wedgwood jw472t@nih.gov 301-496-7104
Biomarkers to measure risk, disease activity, and therapeutic response in autoimmune diseases. Josiah Wedgwood jw472t@nih.gov 301-496-7104
High throughput assay of T-cell activity in autoimmune diseases. Josiah Wedgwood jw472t@nih.gov 301-496-7104
Standardized validated diagnostic criteria and outcome measures for autoimmune diseases correlated with disease activity. Josiah Wedgwood jw472t@nih.gov 301-496-7104
Innovative treatments for primary immunodeficiencies. Josiah Wedgwood jw472t@nih.gov 301-496-7104
Diagnostic tests to identify or screen for primary immunodeficiencies. Josiah Wedgwood jw472t@nih.gov 301-496-7104
Immunotherapeutic antibodies and agents against bioterriorism pathogens (Category A-C). Helen Quill hq1t@nih.gov 301-496-7551
Biomarkers of host immune defense to bioterriorism pathogens (Category A-C). Helen Quill hq1t@nih.gov 301-496-7551
Single cell assay for study of human immunology. Helen Quill hq1t@nih.gov 301-496-7551
Methods and analysis tools to facilitate high throughput, high resolution MHC typing in humans and non-human primates. Kristy Kraemer kkraemer@niaid.nih.gov 301-496-5598
Immunomodulatory agents to prevent graft rejection and biomarkers to predict transplantation outcomes. Nancy Bridges nbridges@niaid.nih.gov 301-496-5598

Source animals, reagents, and diagnostic tools for xenotransplantation

Crystal Koh ckoh@niaid.nih.gov 301-496-5598

Division of Microbiology and Infectious Diseases -- Small Business High-Priority Areas of Interest

Updated December 26, 2007.

Areas of Interest Contact Email Phone

Vaccines for NIAID Category A, B, and C priority pathogens including influenza, Ebola, Marburg, arenavirus, and other viral encephalitides.

Barbara Mulach bm244j@nih.gov 301-496-1884

Vaccine development for tuberculosis, STIs, hepatitis B and C, and malaria and other high-impact global parasitic diseases.

Barbara Mulach bm244j@nih.gov 301-496-1884

Vaccine enhancement and formulation technologies with the goal of providing protection against multiple infectious disease agents, providing accelerated immune responses (more rapid schedules or reduced number of immunizations), increase ease of administration (i.e., self-administration), and increase product stability to minimize cold chain requirements.

Barbara Mulach bm244j@nih.gov 301-496-1884

Therapeutics for NIAID Category A, B, and C priority pathogens including smallpox, viral hemorrhagic fevers, viral encephalitides, botulinum neurotoxins, and influenza.

Barbara Mulach bm244j@nih.gov 301-496-1884

Therapeutics for tuberculosis, hepatitis B and C, and malaria and other high-impact global parasitic diseases.

Barbara Mulach bm244j@nih.gov 301-496-1884

Therapeutics exhibiting broad-spectrum activity against microbial pathogens.

Barbara Mulach bm244j@nih.gov 301-496-1884

Therapeutic enhancement and formulation technologies with the goal of improving drug development timeframes, productivity, efficacy, specificity, safety, stability, and delivery.

Barbara Mulach bm244j@nih.gov 301-496-1884

Diagnostics for point-of-care applications for NIAID Category A, B, and C priority pathogens including influenza and those causing emerging and re-emerging infectious diseases.

Barbara Mulach bm244j@nih.gov 301-496-1884

Diagnostics for tuberculosis, STIs, community acquired pneumonia, and malaria and other high impact, global parasitic diseases.

Barbara Mulach bm244j@nih.gov 301-496-1884

 

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