| | Other Issues: previous | next | latest | archiveCommentary Are biologics more effective than classical disease-modifying antirheumatic drugs? Michael T Nurmohamed and Ben AC Dijkmans PMCID: PMC2592779 Editorials Lipooxygenase inhibition in osteoarthritis: a potential symptomatic and disease modifying effect? Maxime Dougados PMCID: PMC2592778 An important step towards completing the rheumatoid arthritis cycle Walther J van Venrooij and Ger JM Pruijn PMCID: PMC2592789 Introducing Arthritis Research & Therapy's 10th anniversary issue, 'The Scientific Basis of Rheumatology: A Decade of Progress' Iain Hrynaszkiewicz, Peter E Lipsky, and Ravinder N Maini PMCID: PMC2592806 Serum urate, menopause, and postmenopausal hormone use: from eminence to evidence-based medicine Angelo L Gaffo and Kenneth G Saag PMCID: PMC2592808 High-density lipoprotein: does it have a dark side? Joan M Von Feldt PMCID: PMC2592810 Research Articles A polymorphism in the human serotonin 5-HT2A receptor gene may protect against systemic sclerosis by reducing platelet aggregation Lorenzo Beretta, Marta Cossu, Maurizio Marchini, Francesca Cappiello, Andrea Artoni, Giovanna Motta, and Raffaella Scorza PMCID: PMC2592780 The relationship between inflammation and new bone formation in patients with ankylosing spondylitis Xenofon Baraliakos, Joachim Listing, Martin Rudwaleit, Joachim Sieper, and Juergen Braun PMCID: PMC2592781 Elevated autoantibody content in rheumatoid arthritis synovia with lymphoid aggregates and the effect of rituximab Sanna Rosengren, Nathan Wei, Kenneth C Kalunian, Nathan J Zvaifler, Arthur Kavanaugh, and David L Boyle PMCID: PMC2592782 Prognostic factors of 10-year radiographic outcome in early rheumatoid arthritis: a prospective study Natacha Courvoisier, Maxime Dougados, Alain Cantagrel, Philippe Goupille, Olivier Meyer, Jean Sibilia, Jean Pierre Daures, and Bernard Combe PMCID: PMC2592783 4-Hydroxynonenal induces apoptosis in human osteoarthritic chondrocytes: the protective role of glutathione-S-transferase France Vaillancourt, Hassan Fahmi, Qin Shi, Patrick Lavigne, Pierre Ranger, Julio C Fernandes, and Mohamed Benderdour PMCID: PMC2592788 Reduced proportions of natural killer T cells are present in the relatives of lupus patients and are associated with autoimmunity Joan Wither, Yong-chun Cai, Sooyeol Lim, Tamara McKenzie, Nicole Roslin, Jaime O Claudio, Glinda S Cooper, Thomas J Hudson, Andrew D Paterson, Celia MT Greenwood, Dafna Gladman, Janet Pope, Christian A Pineau, C Douglas Smith, John G Hanly, Christine Peschken, Gilles Boire, CaNIOS Investigators, and Paul R Fortin PMCID: PMC2592790 Biologic activity and safety of belimumab, a neutralizing anti-B-lymphocyte stimulator (BLyS) monoclonal antibody: a phase I trial in patients with systemic lupus erythematosus Richard Furie, William Stohl, Ellen M Ginzler, Michael Becker, Nilamadhab Mishra, Winn Chatham, Joan T Merrill, Arthur Weinstein, W Joseph McCune, John Zhong, Wendy Cai, William Freimuth, and the Belimumab Study Group PMCID: PMC2592791 Natural autoantibodies reactive with glycosaminoglycans in rheumatoid arthritis Bence György, László Tóthfalusi, György Nagy, Mária Pásztói, Pál Géher, Zsolt Lörinc, Anna Polgár, Bernadett Rojkovich, Ilona Ujfalussy, Gyula Poór, Péter Pócza, Zoltán Wiener, Petra Misják, Agnes Koncz, András Falus, and Edit I Buzás PMCID: PMC2592792 Role of hypoxia-inducible factor 1alpha in the integrity of articular cartilage in murine knee joints Kolja Gelse, David Pfander, Simon Obier, Karl X Knaup, Michael Wiesener, Friedrich F Hennig, and Bernd Swoboda PMCID: PMC2592793 Association of elevated transcript levels of interferon-inducible chemokines with disease activity and organ damage in systemic lupus erythematosus patients Qiong Fu, Xiaoqing Chen, Huijuan Cui, Yanzhi Guo, Jing Chen, Nan Shen, and Chunde Bao PMCID: PMC2592795 Role of STAT4 polymorphisms in systemic lupus erythematosus in a Japanese population: a case-control association study of the STAT1-STAT4 region Aya Kawasaki, Ikue Ito, Koki Hikami, Jun Ohashi, Taichi Hayashi, Daisuke Goto, Isao Matsumoto, Satoshi Ito, Akito Tsutsumi, Minori Koga, Tadao Arinami, Robert R Graham, Geoffrey Hom, Yoshinari Takasaki, Hiroshi Hashimoto, Timothy W Behrens, Takayuki Sumida, and Naoyuki Tsuchiya PMCID: PMC2592800 Myeloid dendritic cells display downregulation of C-type lectin receptors and aberrant lectin uptake in systemic lupus erythematosus Seetha U Monrad, Kristine Rea, Seth Thacker, and Mariana J Kaplan PMCID: PMC2592801 Dynamic activation of bone morphogenetic protein signaling in collagen-induced arthritis supports their role in joint homeostasis and disease Melina Daans, Rik JU Lories, and Frank P Luyten PMCID: PMC2592802 Menopause, postmenopausal hormone use and serum uric acid levels in US women – The Third National Health and Nutrition Examination Survey A Elisabeth Hak and Hyon K Choi PMCID: PMC2592803 Decreased levels of the gelsolin plasma isoform in patients with rheumatoid arthritis Teresia M Osborn, Margareta Verdrengh, Thomas P Stossel, Andrej Tarkowski, and Maria Bokarewa PMCID: PMC2592804 Weekly intra-articular injections of bone morphogenetic protein-7 inhibits osteoarthritis progression Masaya Hayashi, Takeshi Muneta, Young-Jin Ju, Tomoyuki Mochizuki, and Ichiro Sekiya PMCID: PMC2592805 Epitope spreading to citrullinated antigens in mouse models of autoimmune arthritis and demyelination Brian A Kidd, Peggy P Ho, Orr Sharpe, Xiaoyan Zhao, Beren H Tomooka, Jennifer L Kanter, Lawrence Steinman, and William H Robinson PMCID: PMC2592807 Rationale for prostaglandin I2 in bone marrow oedema – from theory to application Marcus Jäger, Frank Peter Tillmann, Thomas S Thornhill, Marcus Mahmoudi, Dirk Blondin, Gerd Rüdiger Hetzel, Christoph Zilkens, and Rüdiger Krauspe PMCID: PMC2592809 Toll-like receptor homolog RP105 modulates the antigen-presenting cell function and regulates the development of collagen-induced arthritis Yoshifumi Tada, Syuichi Koarada, Fumitaka Morito, Mio Mitamura, Hisako Inoue, Rie Suematsu, Akihide Ohta, Kensuke Miyake, and Kohei Nagasawa PMCID: PMC2592811 Therapeutic effect of the potent IL-12/IL-23 inhibitor STA-5326 on experimental autoimmune uveoretinitis Hiroshi Keino, Takayo Watanabe, Yasuhiko Sato, Mamoru Niikura, Yumiko Wada, and Annabelle A Okada PMCID: PMC2592812 Vitamin D deficiency in undifferentiated connective tissue disease Eva Zold, Peter Szodoray, Janos Gaal, János Kappelmayer, Laszlo Csathy, Edit Gyimesi, Margit Zeher, Gyula Szegedi, and Edit Bodolay PMCID: PMC2592813 Effects of cyclophosphamide on pulmonary function in patients with scleroderma and interstitial lung disease: a systematic review and meta-analysis of randomized controlled trials and observational prospective cohort studies Carlotta Nannini, Colin P West, Patricia J Erwin, and Eric L Matteson PMCID: PMC2592814 Serum levels of biomarkers of bone and cartilage destruction and new bone formation in different cohorts of patients with axial spondyloarthritis with and without tumor necrosis factor-alpha blocker treatment Heiner Appel, Louise Janssen, Joachim Listing, René Heydrich, Martin Rudwaleit, and Joachim Sieper PMCID: PMC2592815 Association of a single nucleotide polymorphism in growth differentiate factor 5 with congenital dysplasia of the hip: a case-control study Jin Dai, Dongquan Shi, Pengsheng Zhu, Jianghui Qin, Haijian Ni, Yong Xu, Chen Yao, Lunqing Zhu, Hongtao Zhu, Baocheng Zhao, Jia Wei, Baorui Liu, Shiro Ikegawa, Qing Jiang, and Yitao Ding PMCID: PMC2592816 Reviews Genetic studies in osteoporosis – the end of the beginning Emma L Duncan and Matthew A Brown PMCID: PMC2592817 Virally associated arthritis 2008: clinical, epidemiologic, and pathophysiologic considerations Dimitrios Vassilopoulos and Leonard H Calabrese PMCID: PMC2592818 Cell signalling in macrophages, the principal innate immune effector cells of rheumatoid arthritis Stefan K Drexler, Philip L Kong, Jeremy Wales, and Brian M Foxwell PMCID: PMC2592774 Stem cell transplantation for rheumatic autoimmune diseases Thomas Hügle and Jacob M van Laar PMCID: PMC2592775 Developments in the scientific understanding of lupus Stacy P Ardoin and David S Pisetsky PMCID: PMC2592776 Epigenetic modifications in rheumatoid arthritis Simon Strietholt, Britta Maurer, Marvin A Peters, Thomas Pap, and Steffen Gay PMCID: PMC2592785 Developments in the scientific and clinical understanding of inflammatory myopathies Ingrid E Lundberg and Cecilia Grundtman PMCID: PMC2592786 Developments in the scientific and clinical understanding of gout Alexander So PMCID: PMC2592794 What magnetic resonance imaging has told us about the pathogenesis of rheumatoid arthritis – the first 50 years Dennis McGonagle and Ai Lyn Tan PMCID: PMC2592796 Mesenchymal stem cells in arthritic diseases Faye H Chen and Rocky S Tuan PMCID: PMC2592798 Vascular involvement in rheumatic diseases: 'vascular rheumatology' Zoltán Szekanecz and Alisa E Koch PMCID: PMC2592799 Immune regulation of bone loss by Th17 cells Iannis E Adamopoulos and Edward P Bowman PMCID: PMC2592787 Targeting histone deacetylase activity in rheumatoid arthritis and asthma as prototypes of inflammatory disease: should we keep our HATs on? Aleksander M Grabiec, Paul P Tak, and Kris A Reedquist PMCID: PMC2592777 Corrections Correction: Initial clinical trial of epratuzumab (humanized anti-CD22 antibody) for immunotherapy of systemic lupus erythematosus Thomas Dörner, Joerg Kaufmann, William A Wegener, Nick Teoh, David M Goldenberg, and Gerd R Burmester PMCID: PMC2592784 Corrects: Thomas Dörner, et al. Initial clinical trial of epratuzumab (humanized anti-CD22 antibody) for immunotherapy of systemic lupus erythematosus. Arthritis Res Ther. 2006; 8(3): R74. Correction: Forced mobilization accelerates pathogenesis: characterization of a preclinical surgical model of osteoarthritis C Thomas G Appleton, David D McErlain, Vasek Pitelka, Neil Schwartz, Suzanne M Bernier, James L Henry, David W Holdsworth, and Frank Beier PMCID: PMC2592797 Corrects: C Thomas G Appleton, et al. Forced mobilization accelerates pathogenesis: characterization of a preclinical surgical model of osteoarthritis. Arthritis Res Ther. 2007; 9(1): R13. |
