[TTT Membership Roster] [TTT Meeting Rosters]

The Transplantation, Tolerance and Tumor Immunology (TTT) Study Section reviews applications involving the making and breaking of immune tolerance.  This includes human and animal studies of immune-mediated transplant rejection, basic mechanisms of acquired immune tolerance, and studies of tumor immunology and vaccine development.  Emphasis is on immune mechanisms.  Specific areas covered by TTT:

• Transplantation:  studies of transplant rejection when the major focus is on the immune response to the transplanted organ and immune mechanisms behind immunosuppressive drugs and therapies for prevention of transplant rejection; solid organ and hematopoietic transplant tolerance, in both small and large animal models as well as clinical studies and clinical trials; mechanisms of development and strategies for prevention of graft vs. host disease, including promotion of graft vs. tumor/leukemia effects.
• Tolerance:  mechanisms of immune tolerance, both central and peripheral, using a variety of systems including engineered mice and tumor, autoimmune, or transplant models.
• Tumor Immunology:  immune surveillance, mechanisms of immune evasion, or immune suppression in the tumor microenvironment, in both humans and animal models; identification of new tumor associated antigens; early stage development and testing of tumor vaccines in animal models.

Study sections with the most closely related areas of science listed in rank order are:

Cancer Immunopathology and Immunotherapy (CII) 
Hypersensitivity, Autoimmune, and Immune-Mediated Diseases (HAI) 
Cellular and Molecular Immunology A (CMIA) 
Cellular and Molecular Immunology B (CMIB) 
Innate Immunity and Inflammation (III)