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Roderic Pettigrew, Ph.D., M.D. Director Democracy Plaza II, Suite 200 Tel: 301-496-8859 Fax: 301-480-4973 E-mail: pettigrr@mail.nih.gov

Roderic I. Pettigrew, Ph.D., M.D., is the first Director of the National Institute of Biomedical Imaging and Bioengineering. Prior to his appointment, he was a Professor of Radiology Medicine (Cardiology) at Emory University, as well as Professor of Bioengineering at the Georgia Institute of Technology. He also served as Director of the Emory Center for Magnetic Resonance (MR) Research at Emory University School of Medicine in Atlanta, Georgia.

Dr. Pettigrew is known for his pioneering research at Emory University involving four-dimensional imaging of the heart using MR. He graduated cum laude with a B.S. in Physics from Morehouse College where he was a Merrill Scholar. He received an M.S. in Nuclear Science and Engineering from Rennselear Polytechnic Institute, and he received a Ph.D. in Applied Radiation Physics from the Massachusetts Institute of Technology as a Whitaker Harvard-MIT Health Sciences Scholar. Subsequently, he received an M.D. from the University of Miami School of Medicine in an accelerated two-year program, served an internship and residency in Internal Medicine at Emory University, and completed his residency in Nuclear Medicine at the University of California, San Diego. Dr. Pettigrew then spent a year as a Clinical Research Scientist with Picker International, the first manufacturer of MR equipment. In 1985, he joined Emory as a Robert Wood Johnson Foundation Fellow focusing in non-invasive cardiac imaging.

Dr. Pettigrew's awards include membership in Phi Beta Kappa, the Bennie Award (Benjamin E. Mays) for Achievement, and he was named the Most Distinguished Alumnus of the University of Miami. In 1989, when the Radiological Society of North America met to celebrate its 75th (Diamond) Anniversary, Dr. Pettigrew was selected to give the keynote Eugene P. Pendergrass New Horizons Lecture. He has served as Chairman of the Diagnostic Radiology Study Section for the Center for Scientific Review at NIH, and has been elected to membership in the Institute of Medicine and fellowships in the American Heart Association, the American College of Cardiology, the American Institute for Medical and Biological Engineering, the International Society for Magnetic Resonance in Medicine, and the Biomedical Engineering Society.

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 Scientific Publications

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| 1994 | 1993 | 1992 | 1991 | 1990 | 1989 | 1988 | 1987 | 1986 | 1985 | 1984 | 

2006

Alexander DF, Alving BM, Battey JF, Berg JM, Collins FS, Fauci AS, Gallin JI, Grady PA, Hodes RJ, Hrynkow SH, Insel TR, Jones JF, Katz SI, Landis SC, Li TK, Lindberg DA, Nabel EG, Niederhuber JE, Pettigrew RI, Rodgers GP, Ruffin J, Scarpa A, Schwartz DA, Sieving PA, Straus SE, Tabak LA, Volkow ND. Response to: "Rescuing the NIH before it is too late." J Clin Invest Apr 28, 2006.

Nezafat R, Stuber M, Ouwerkerk R, Gharib AM, Desai MY, Pettigrew RI. B1-insensitive T2 preparation for improved coronary magnetic resonance angiography at 3 T. Magn Reson Med 55(4):858-64, 2006.

Sharma P, Socolow J, Patel S, Pettigrew RI, Oshinski JN. Effect of Gd-DTPA-BMA on blood and myocardial T1 at 1.5T and 3T in humans. J Magn Reson Imaging 23(3):323-30, 2006.

2005

Seto DB, McLaughlin A, Li K, Menkens A, Sullivan D, Pettigrew R. Advancing the Boundaries of Molecular Imaging. Biol Psychiatry Sep 13, 2005.

Simor T, Gaszner B, Oshinski JN, Waldrop SM, Pettigrew RI, Horvath IG, Hild G, Elgavish GA. Gd(ABE-DTTA)-enhanced cardiac MRI for the diagnosis of ischemic events in the heart. J Magn Reson Imaging 21(5):536-45, 2005. 

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2004

Pettigrew RI, Fee CA, Li KC. Changes in the world of biomedical research are moving the field of "personalized medicine" from concept to reality. J Nucl Med 45(9):1427, 2004.

Johnson KR, Patel SJ, Whigham A, Hakim A, Pettigrew RI, Oshinski JN. Three-dimensional, time-resolved motion of the coronary arteries. J Cardiovasc Magn Reson 6(3):663-73, 2004. 

Muthupillai R, Flamm SD, Wilson JM, Pettigrew RI, Dixon WT. Acute myocardial infarction: tissue characterization with T1rho-weighted MR imaging--initial experience. Radiology 232(2):606-10, 2004. 

Brummer ME, Moratal-Perez D, Hong CY, Pettigrew RI, Millet-Roig J, Dixon WT. Noquist: reduced field-of-view imaging by direct Fourier inversion. Magn Reson Med 51(2):331-42, 2004.

2003

Fee CA, Pettigrew RI. National Institute of Biomedical Imaging and Bioengineering: poised for the future. Radiology 229(3):636-7, 2003.

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2002

Han HC, Oshinski JN, Ku DN, Pettigrew RI. A left ventricle model to predict post-revascularization ejection fraction based on cine magnetic resonance images. J Biomech Eng 124(1):52-5, 2002.

2001

Faber TL, Vansant JP, Pettigrew RI, Galt JR, Blais M, Chatzimavroudis G, Cooke CD, Folks RD, Waldrop SM, Gurtler-Krawczynska E, Wittry MD, Garcia EV. Evaluation of left ventricular endocardial volumes and ejection fractions computed from gated perfusion SPECT with magnetic resonance imaging: comparison of two methods. J Nucl Cardiol 8(6):645-51, 2001.

Oshinski JN, Han HC, Ku DN, Pettigrew RI. Quantitative prediction of improvement in cardiac function after revascularization with MR imaging and modeling: initial results. Radiology 221(2):515-22, 2001.

Chatzimavroudis GP, Oshinski JN, Franch RH, Walker PG, Yoganathan AP, Pettigrew RI. Evaluation of the precision of magnetic resonance phase velocity mapping for blood flow measurements. J Cardiovasc Magn Reson 3(1):11-9, 2001.

Videlefsky N, Parks WJ, Oshinski J, Hopkins KL, Sullivan KM, Pettigrew RI, Fyfe D. Magnetic resonance phase-shift velocity mapping in pediatric patients with pulmonary venous obstruction. J Am Coll Cardiol 38(1):262-7, 2001.

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2000

Ensley AE, Ramuzat A, Healy TM, Chatzimavroudis GP, Lucas C, Sharma S, Pettigrew R, Yoganathan AP. Fluid mechanic assessment of the total cavopulmonary connection using magnetic resonance phase velocity mapping and digital particle image velocimetry. Ann Biomed Eng 28(10):1172-83, 2000.

Laham RJ, Chronos NA, Pike M, Leimbach ME, Udelson JE, Pearlman JD, Pettigrew RI, Whitehouse MJ, Yoshizawa C, Simons M. Intracoronary basic fibroblast growth factor (FGF-2) in patients with severe ischemic heart disease: results of a phase I open-label dose escalation study. J Am Coll Cardiol 36(7):2132-9, 2000.

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1999

Faber TL, Cooke CD, Folks RD, Vansant JP, Nichols KJ, DePuey EG, Pettigrew RI, Garcia EV. Left ventricular function and perfusion from gated SPECT perfusion images: an integrated method. J Nucl Med 40(4):650-9, 1999.

Oshinski JN, Franch R, Shirazi SH, Pettigrew RI. Use of navigator-echo-gated MRI to diagnose a coronary shunt involving an anomalous origin of the right coronary artery from the pulmonary artery. J Magn Reson Imaging 9(5):738-40, 1999.

Bom HS, Vansant JP, Pettigrew RI, Cooke CD, Votaw JR, Garcia EV. Determination of Myocardial Viability with ECG-Gated Fluorodeoxyglucose F-18 Positron Emission Tomography. Clin Positron Imaging. 2(4):183-190, 1999.

Pettigrew RI, Oshinski JN, Chatzimavroudis G, Dixon WT. MRI techniques for cardiovascular imaging. J Magn Reson Imaging 10(5):590-601, 1999.

Alazraki NP, Krawczynska EG, Kosinski AS, DePuey EG 3rd, Ziffer JA, Taylor AT Jr, Pettigrew RI, Vansant JP, Shaw LJ, Weintraub WS, King SB 3rd. Prognostic value of thallium-201 single-photon emission computed tomography for patients with multivessel coronary artery disease after revascularization (the Emory Angioplasty versus Surgery Trial [EAST]). Am J Cardiol 84(12):1369-74, 1999.

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1998

Chatzimavroudis GP, Oshinski JN, Franch RH, Pettigrew RI, Walker PG, Yoganathan AP. Quantification of the aortic regurgitant volume with magnetic resonance phase velocity mapping: a clinical investigation of the importance of imaging slice location. J Heart Valve Dis 7(1):94-101, 1998.

Chatzimavroudis GP, Oshinski JN, Pettigrew RI, Walker PG, Franch RH, Yoganathan AP. Quantification of mitral regurgitation with MR phase-velocity mapping using a control volume method. J Magn Reson Imaging 8(3):577-82, 1998.

Oshinski JN, Hofland L, Dixon WT, Pettigrew RI. Magnetic resonance coronary angiography using navigator echo gated real-time slice following. Int J Card Imaging 14(3):191-9, 1998. 

Budinger TF, Berson A, McVeigh ER, Pettigrew RI, Pohost GM, Watson JT, Wickline SA. Cardiac MR imaging: report of a working group sponsored by the National Heart, Lung, and Blood Institute. Radiology 208(3):573-6, 1998.

Oshinski J, Franch R, Baron M, Pettigrew R. Images in cardiovascular medicine. Austin Flint murmur. Circulation 98(24):2782-3, 1998.

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1997

Orr LA, Pettigrew RI, Churchwell AL, Jennings HS 3rd, Petracek MR, Vansant JP. Gadolinium utilization in the MR evaluation of cardiac paraganglioma. Clin Imaging 21(6):404-6, 1997.

Chatzimavroudis GP, Walker PG, Oshinski JN, Franch RH, Pettigrew RI, Yoganathan AP. The importance of slice location on the accuracy of aortic regurgitation measurements with magnetic resonance phase velocity mapping. Ann Biomed Eng 25(4):644-52, 1997.

Siegel JM Jr, Oshinski JN, Pettigrew RI, Ku DN. Computational simulation of turbulent signal loss in 2D time-of-flight magnetic resonance angiograms. Magn Reson Med 37(4):609-14, 1997.

Chatzimavroudis GP, Walker PG, Oshinski JN, Franch RH, Pettigrew RI, Yoganathan AP. Slice location dependence of aortic regurgitation measurements with MR phase velocity mapping. Magn Reson Med 37(4):545-51, 1997.

Halkar R, Pettigrew R, Lipman C, Gilles L. Rapid transit of tracer to the kidneys and urinary bladder in radionuclide cisternography. A sign of CSF leak. Clin Nucl Med 22(2):121-3, 1997.

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1996

Oshinski JN, Parks WJ, Markou CP, Bergman HL, Larson BE, Ku DN, Mukundan S Jr, Pettigrew RI. Improved measurement of pressure gradients in aortic coarctation by magnetic resonance imaging. J Am Coll Cardiol 28(7):1818-26, 1996.

Chandra M, Pettigrew RI, Eley JW, Oshinski JN, Guyton RA. Cine-MRI-aided endomyocardectomy in idiopathic hypereosinophilic syndrome. Ann Thorac Surg 62(6):1856-8, 1996.

Siegel JM Jr, Oshinski JN, Pettigrew RI, Ku DN. The accuracy of magnetic resonance phase velocity measurements in stenotic flow. J Biomech 29(12):1665-72, 1996. 

Oshinski JN, Hofland L, Mukundan S Jr, Dixon WT, Parks WJ, Pettigrew RI. Two-dimensional coronary MR angiography without breath holding. Radiology 201(3):737-43, 1996.

Chandra M, Silverman ME, Oshinski J, Pettigrew R. Diagnosis of cardiac sarcoidosis aided by MRI. Chest. 1996 Aug;110(2):562-5.

Dixon WT, Oshinski JN, Trudeau JD, Arnold BC, Pettigrew RI. Myocardial suppression in vivo by spin locking with composite pulses. Magn Reson Med 36(1):90-4, 1996.

Cecil MP, Kosinski AS, Jones MT, Taylor A, Alazraki NP, Pettigrew RI, Weintraub WS. The importance of work-up (verification) bias correction in assessing the accuracy of SPECT thallium-201 testing for the diagnosis of coronary artery disease. J Clin Epidemiol 49(7):735-42, 1996.

Ehman RL, Crues JV, Lenkinski RE, Lomas DJ, McVeigh ER, Mitchell DG, Outwater EM, Pettigrew RI, Ross JR. Magnetic resonance. Radiology 198(3):920-6, 1996.

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1995

Siegel JM Jr, Oshinski JN, Pettigrew RI, Ku DN. Comparison of phantom and computer-simulated MR images of flow in a convergent geometry: implications for improved two-dimensional MR angiography. J Magn Reson Imaging 5(6):677-83, 1995.

Oshinski JN, Ku DN, Mukundan S Jr, Loth F, Pettigrew RI. Determination of wall shear stress in the aorta with the use of MR phase velocity mapping. J Magn Reson Imaging 5(6):640-7, 1995.

Parks WJ, Ngo TD, Plauth WH Jr, Bank ER, Sheppard SK, Pettigrew RI, Williams WH. Incidence of aneurysm formation after Dacron patch aortoplasty repair for coarctation of the aorta: long-term results and assessment utilizing magnetic resonance angiography with three-dimensional surface rendering. J Am Coll Cardiol 26(1):266-71, 1995.

Faber TL, Cooke CD, Peifer JW, Pettigrew RI, Vansant JP, Leyendecker JR, Garcia EV. Three-dimensional displays of left ventricular epicardial surface from standard cardiac SPECT perfusion quantification techniques. J Nucl Med 36(4):697-703, 1995.

Oshinski JN, Ku DN, Pettigrew RI. Turbulent fluctuation velocity: the most significant determinant of signal loss in stenotic vessels. Magn Reson Med 33(2):193-9, 1995.

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1994

Alazraki NP, Krawczynska EG, DePuey EG, Ziffer JA, Vansant JP, Pettigrew RI, Taylor A, King SB 3rd, Garcia EV. Reproducibility of thallium-201 exercise SPECT studies. J Nucl Med 35(8):1237-44, 1994.

Cooke CD, Garcia EV, Cullom SJ, Faber TL, Pettigrew RI. Determining the accuracy of calculating systolic wall thickening using a fast Fourier transform approximation: a simulation study based on canine and patient data. J Nucl Med 35(7):1185-92, 1994.

Scott NA, Pettigrew RI. Absence of movement of coronary stents after placement in a magnetic resonance imaging field. Am J Cardiol 73(12):900-1, 1994.

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1993

Pettigrew RI, Cecil MP. Basic cardiovascular magnetic resonance imaging techniques. Coron Artery Dis 4(4):318-27, 1993.

Fleagle SR, Thedens DR, Stanford W, Pettigrew RI, Reichek N, Skorton DJ. Multicenter trial of automated border detection in cardiac MR imaging. J Magn Reson Imaging 3(2):409-15, 1993.

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1992

Oshinski JN, Ku DN, Bohning DE, Pettigrew RI. Effects of acceleration on the accuracy of MR phase velocity measurements. J Magn Reson Imaging 2(6):665-70, 1992.

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1991

Pettigrew RI. Dynamic magnetic resonance imaging in acquired heart disease. Semin Ultrasound CT MR 12(1):61-91, 1991.

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1990

Ku DN, Biancheri CL, Pettigrew RI, Peifer JW, Markou CP, Engels H. Evaluation of magnetic resonance velocimetry for steady flow. J Biomech Eng 112(4):464-72, 1990.

Klein JL, Garcia EV, DePuey EG, Campbell J, Taylor AT, Pettigrew RI, D'Amato P, Folks R, Alazraki N. Reversibility bull's-eye: a new polar bull's-eye map to quantify reversibility of stress-induced SPECT thallium-201 myocardial perfusion defects. J Nucl Med 31(7):1240-6, 1990.

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1989

Pettigrew RI. Dynamic cardiac MR imaging. Techniques and applications. Radiol Clin North Am 27(6):1183-203, 1989. 

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1988

Eisner RL, Fajman WA, Nowak DJ, Pettigrew RI. Improved image quality with elliptical orbits and distance-weighted backprojection SPECT reconstruction. Ann Nucl Med 2(2):107-10, 1988.  

Kolla IS, Kell M, Pettigrew R. Donor indium-111 leukocyte scan in a nonleukopenic patient. Clin Nucl Med 13(7):529-30, 1988.

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1987

Pettigrew RI, Dannels W. Use of standard gradients with compound oblique angulation for optimal quantitative MR flow imaging in oblique vessels. AJR Am J Roentgenol 148(2):405-9, 1987. 

Pettigrew RI, Dannels W, Galloway JR, Pearson T, Millikan W, Henderson JM, Peterson J, Bernardino ME. Quantitative phase-flow MR imaging in dogs by using standard sequences: comparison with in vivo flow-meter measurements. AJR Am J Roentgenol 148(2):411-4, 1987.

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1986

Eisner RL, Nowak DJ, Pettigrew R, Fajman W. Fundamentals of 180 degree acquisition and reconstruction in SPECT imaging. J Nucl Med 27(11):1717-28, 1986.

Pettigrew RI, Avruch L, Dannels W, Coumans J, Bernardino ME. Fast-field-echo MR imaging with Gd-DTPA: physiologic evaluation of the kidney and liver. Radiology 160(2):561-3, 1986. 

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1985

Braun IF, Hoffman JC Jr, Malko JA, Pettigrew RI, Dannels W, Davis PC. Jugular venous thrombosis: MR imaging. Radiology 157(2):357-60, 1985.

Berger HJ, Pettigrew RI. The future of cardiovascular imaging: a shift from anatomy to in vivo biochemistry. J Am Coll Cardiol 5(3):750-3, 1985.

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1984

Pettigrew RI, Witztum KF, Perkins GC, Johnson ML, Burks RN, Verba JW, Halpern SE. Single photon emission computed tomograms of the liver: normal vascular intrahepatic structures. Radiology 150(1):219-23, 1984. 

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