Procalcitonin Increase Identifies Critically Ill Patients at High Risk of Mortality

This study has been completed.

Sponsored by:	Danish Procalcitonin Study Group
Information provided by:	Danish Procalcitonin Study Group
ClinicalTrials.gov Identifier:	NCT00144638

Purpose

Procalcitonin, a marker of infection has often been compared to clinical pictures as for instance "clinical sepsis". This has given som problems in the interpretation of these studies, because of the lack of good Gold Standards for "clinical sepsis. We have decided to investigate the development from day to day of Procalcitonin in the blood of intensive care patients, compared to the mortality.

Hypothesis: Procalcitonin increase after reaching a certain level predicts mortality in the Intensive Care Unit.

Condition
Sepsis - to Reduce Mortality in the Intensive Care Unit

MedlinePlus related topics: Sepsis

Drug Information available for: Procalcitonin

U.S. FDA Resources

Study Type:	Observational
Study Design:	Natural History, Longitudinal, Defined Population, Prospective Study
Official Title:	Procalcitonin Increase Identifies Critically Ill Patients at High Risk of Mortality

Further study details as provided by Danish Procalcitonin Study Group:

Estimated Enrollment:	450
Study Start Date:	January 2002
Estimated Study Completion Date:	January 2003

Show Detailed Description

Eligibility

Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria: Admitted to the ICU 4131 of Rigshospitalet Copenhagen University Hospital in the year 2002

Exclusion Criteria:

Recent (< 3 months) liver transplantation

Expected admission < 24 h

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00144638

Locations

Denmark
Dept. 4131, Rigshospitalet, Cph University Hosp., DK
Copenhagen, Denmark, DK-2100

Sponsors and Collaborators

Danish Procalcitonin Study Group

Investigators

Principal Investigator:

Lars Heslet, MD, MD.Sc.

Dept. 4131, Rigshospitalet, Blegdamsvej 9, DK-2100

More Information

Study ID Numbers:	DPSG1
Study First Received:	September 1, 2005
Last Updated:	September 1, 2005
ClinicalTrials.gov Identifier:	NCT00144638
Health Authority:	Denmark: National Board of Health

Study placed in the following topic categories:

Sepsis
Critical Illness

Additional relevant MeSH terms:

Disease Attributes
Pathologic Processes

ClinicalTrials.gov processed this record on January 16, 2009