Inclusion Criteria:

Written informed consent, male or female patients 40 years of age or older, smoking history of at least 10 pack years, diagnosis of COPD with post bronchodilator FEV1 less than or equal to 70% of predicted normal and FEV1<70% of FVC and on stable respiratory medication

Exclusion Criteria:

Significant diseases other than COPD which in the opinion of the investigator may put the patient at risk or influence the patients ability to participate, Mi in past 6 months, unstable or life threatening arrhythmia in past year, hospitalization for NYHA heart failure class III or IV in past year, active TB, asthma, pulmonary resection, malignancy treated with radiation or chemotherapy in past 5 years, respiratory infection in 4 weeks prior to screening, known hypersensitivity to anticholinergic drugs or components, known moderate to severe renal impairment, known narrow angle glaucoma, significant symptomatic BPH or bladder neck obstruction, need for oxygen therapy >12 hr/day, use of oral corticosteroids at unstable doses or >10 mg/day