Home
Search
Study Topics
Glossary
|
|
|
|
|
|
Sponsored by: |
Sunnybrook Health Sciences Centre |
---|---|
Information provided by: | Sunnybrook Health Sciences Centre |
ClinicalTrials.gov Identifier: | NCT00497354 |
Peripheral nerve blocks provide many advantages for patients (excellent pain control and reduction in nausea) undergoing upper and lower limb surgery however several commonly occurring complications can produce annoying but sometimes serious adverse effects. The interscalene brachial plexus block (ISBPB) is one such technique, commonly performed for shoulder surgery, but also produces paralysis of the diaphragm, Horner’s syndrome and sometimes vocal cord paralysis with standard volumes of local anesthetic. This threat of these side effects limits the use of ISBPB in many patients who would particularly benefit e.g. patients with lung disease. Recently the use of ultrasound guidance is allowing practitioners to place smaller volumes of local anesthetic with much greater accuracy. This can potentially avoid anesthetizing important adjacent nerves to the target structure. If ultrasound-guided techniques with smaller volumes of local anesthetic could be demonstrated to reduce the incidence of complications without reducing effectiveness this would be very beneficial for patients.This will be the first randomized, double blind study to evaluate if an ultrasound-guided ISBPB with low volumes of local anesthetic can reduce complications for patients whilst maintaining quality of anesthesia and pain relief in the intra-operative and postoperative period.
Condition | Intervention | Phase |
---|---|---|
Pain After Shoulder Surgery |
Drug: Variation in volume of local anesthetic Procedure: Ultrasound-guided interscalene brachial plexus block |
Phase III |
Study Type: | Interventional |
Study Design: | Treatment, Randomized, Double-Blind, Active Control, Single Group Assignment, Safety/Efficacy Study |
Official Title: | Does a Low Volume Ultrasound-Guided Technique Reduce Common Complications of Interscalene Brachial Plexus Block? |
Ages Eligible for Study: | 18 Years to 70 Years |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
Exclusion Criteria:
Contact: Colin JL McCartney, FRCA | 416 480 6100 ext 3230 | colin.mccartney@utoronto.ca |
Canada, Ontario | |
Sunnybrook Health Sciences Centre | |
Toronto, Ontario, Canada, M5N3M5 |
Principal Investigator: | Colin JL McCartney, FRCA | Sunnybrook Health Sciences Centre |
Study ID Numbers: | SHSCA01 |
Study First Received: | July 3, 2007 |
Last Updated: | July 4, 2007 |
ClinicalTrials.gov Identifier: | NCT00497354 |
Health Authority: | United States: Food and Drug Administration |
Ultrasound, Complications, Regional Anesthesia |
Pain |