Inclusion Criteria:

• Has mild to moderate uncomplicated essential hypertension (diastolic blood pressure between 95 and 114 mm Hg at Screening Day -7 and randomization visit).
• Female patients of childbearing potential must be nonpregnant and nonlactating, and utilizing an acceptable method of contraception.
• Has clinical laboratory evaluations (including clinical chemistry, hematology, and complete urinalysis) within the reference range for the testing laboratory unless the results are deemed not clinically significant for inclusion into this study by the investigator or sponsor.
• Is willing to discontinue current antihypertensive medications.

Exclusion Criteria:

• Has a decrease of more than or equal to 8 mm Hg in clinic diastolic blood pressure between Screening Day -7 and randomization visit.
• Is hypersensitive to angiotensin II receptor blockers.
• The patient has Grade 3 or 4 hypertensive retinopathy (Keith-Wagener scale).
• Has significant cardiac disease (eg, primary, hemodynamically significant cardiac valvular disease) other than mild to moderate uncomplicated hypertensive cardiovascular disease.

• Has taken, within 7 days prior to placebo run-in, or is expected to take, medications known to affect blood pressure, including the following:

  • Diuretics
  • Anti-hypertensives
  • Vasodilators
  • Tricyclic antidepressants
  • Monoamine oxidase inhibitors
  • Phenothiazines
  • Diet medications
  • Amphetamines or their derivatives
  • Thiazolidinediones
  • Lithium
  • Chronic use of common cold medications or nonsteroidal anti-inflammatory drugs including aspirin >325 mg/day or cyclooxygenase-2 inhibitors).
• Has a history of myocardial infarction complicated by heart failure, post-myocardial infarction angina, hypertensive encephalopathy, or cerebrovascular accident.
• Has clinically significant cardiac conduction defects (eg, 2nd or 3rd degree atrioventricular block, left bundle branch block, sick sinus syndrome, atrial fibrillation or flutter).
• Has secondary hypertension of any etiology (eg, renal disease, pheochromocytoma, Cushing's syndrome).
• Has a history of collagen vascular disorder (eg systemic lupus erythematosus, scleroderma) within the last five years.
• Has an upper arm circumference less than 24 or greater than 42 cm.
• Works night (3rd) shift.
• Is non-compliant (less than 80%) with study medication during placebo run-in period.
• Has significant, moderate to severe renal dysfunction or disease (including renal artery stenosis).
• Has a history of drug abuse (defined as illicit drug use) or a history of alcohol abuse (defined as regular or daily consumption of more than 4 alcoholic drinks per day) within the past 2 years.
• Has a previous history of cancer, other than basal cell carcinoma, that has not been in remission for at least 5 years prior to the first dose of study drug.
• Has Type I or Type II diabetes mellitus.
• Has an alanine transaminase or aspartate transaminase level of greater than 3 times the upper limit of normal, active liver disease, or jaundice.
• Is participating in another investigational study or has participated in an investigational study within 30 days prior to randomization.
• Has -any other serious disease or condition at Screening (or randomization) that would compromise patient safety, might affect life expectancy, or make it difficult to successfully manage and follow the patient according to the protocol.