Spatio-Temporal Analyses of the T Cell Response

 


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Air date: Wednesday, March 12, 2008, 4:15:00 PM
Category: Immunology
Description: Max did his Ph.D. with Jim Allison at Berkeley, where he contributed to unraveling the opposing effects of CD28 and CTLA-4 on T cell activation. After a brief stint at the Walter and Eliza Hall Institute in Melbourne, Australia, he returned to the West Coast and spent several years as a fellow in Mark Davis’s lab, where he helped pioneer the application of high-resolution, dynamic single cell imaging to investigation of the immunological synapse and the molecular events involved in antigen-driven T cell activation. In 2001 he started his own laboratory at UCSF, where he expanded his imaging interests from the molecular to the cell level, constructing an improved resonant scanning 2 photon microscope that has served as the platform for his own research and that of many of his UCSF colleagues. He has continued to make important contributions to our understanding of the cell biology of T cell activation, in particular the regulation of synaptic communication and lymphocyte mobility. His talk encompasses these major themes.

The Immunology Interest Group (IIG) organizes activities designed to promote information exchange and interactions among NIH scientists interested in the field of immunology, broadly defined. Interactions are facilitated via weekly meetings on current topics as well as an annual Immunology Retreat.

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Author: Max Krummel, Ph.D., University of California, San Francisco
Runtime: 01:04:56
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CIT File ID: 14357
CIT Live ID: 6145
Permanent link: http://videocast.nih.gov/launch.asp?14357