Prognosis of Atypical Pituitary Adenomas

This study is ongoing, but not recruiting participants.

Sponsored by:	Tohoku University
Information provided by:	Tohoku University
ClinicalTrials.gov Identifier:	NCT00473369

Purpose

Context: Pituitary adenoma is generally indolent, but an aggressive subtype called atypical adenoma has uncertain prognosis, and an unclear relationship between prognosis and morphology.

Objective: This study investigated the prognostic factors of this tumor. Design: Retrospective analysis. Setting: University and associated hospitals.

Condition
Pituitary Diseases

MedlinePlus related topics: Pituitary Disorders

U.S. FDA Resources

Study Type:	Observational
Study Design:	Natural History, Cross-Sectional, Case Control, Retrospective Study

Further study details as provided by Tohoku University:

Study Start Date:	January 2001
Estimated Study Completion Date:	May 2007

Eligibility

Ages Eligible for Study:	12 Years to 74 Years
Genders Eligible for Study:	Both

Criteria

Inclusion Criteria:

pituitary adenomas of more than 3 % of Ki67 labeling index surgically treated at Tohoku university and associated hospital

Exclusion Criteria:

pituitary adenomas of less than 3 % of Ki-67 labeling index surgically treated at Tohoku university and associated hospital

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00473369

Sponsors and Collaborators

Tohoku University

Investigators

Principal Investigator:

Yoshikazu Ogawa, M. D.

Department of neurosurgery, Tohoku university

More Information

Study ID Numbers:	1-2007.nsg.med.tohoku
Study First Received:	May 14, 2007
Last Updated:	May 14, 2007
ClinicalTrials.gov Identifier:	NCT00473369
Health Authority:	Japan: Institutional Review Board

Keywords provided by Tohoku University:

atypical adenoma
Ki-67
p53
pituitary
prognosis

Study placed in the following topic categories:

Hypothalamic Diseases
Pituitary Diseases
Endocrine System Diseases
Central Nervous System Diseases

Endocrinopathy
Brain Diseases
Adenoma

Additional relevant MeSH terms:

Nervous System Diseases

ClinicalTrials.gov processed this record on January 14, 2009