The HIV program in the Division of Kidney, Urologic, and Hematologic Diseases supports basic and clinical studies on renal and genitourinary tract structure and function in individuals with HIV infection. Interests include the pathogenetic mechanisms of viral infection in the kidney and genitourinary tract, and sites of viral replication and/or spread and the resulting organ dysfunction. Studies on HIV infection focus on (1) the effect of HIV therapies on marrow function and clinical course of dialysis and transplant patients, (2) potential interactions of HIV infection and therapies on the immunosuppressive therapy used to prevent transplant rejection and (3) effect of HIV infection and treatment on organ function. An important new emphasis is research into the development of strategies for gene therapy for HIV, using modification of hematopoietic stem cells.
For further information about this program in the area of urology contact Dr. Laura Moen, KUH, Director, Renal and Urology Training Program and Renal Biochemistry Program.