Environmental Treatment for Seasonal Affective Disorder (SAD)

This study has been completed.

Sponsors and Collaborators:	Yale University University of British Columbia University Hospital Royal Ottawa Hospital McGill University Royal University Hospital Foundation
Information provided by:	Yale University
ClinicalTrials.gov Identifier:	NCT00139997

Purpose

The purpose is to study treatments of Seasonal Affective Disorder (SAD).

Condition	Intervention
Seasonal Affective Disorder	Device: Litebook treatment devices

MedlinePlus related topics: Depression Seasonal Affective Disorder

U.S. FDA Resources

Study Type:	Interventional
Study Design:	Treatment, Randomized, Double-Blind, Placebo Control, Parallel Assignment, Safety/Efficacy Study
Official Title:	A Multicenter, Randomized Controlled Trial of Negative Ion Generation Versus Light-Emitting Diode Phototherapy For Seasonal Affective Disorder

Further study details as provided by Yale University:

Primary Outcome Measures:

SIGH SAD (Structured Interview Guide For The Hamilton Depression Rating Scale), SAD version

Estimated Enrollment:	30
Study Start Date:	January 2002
Estimated Study Completion Date:	August 2005

Detailed Description:

This is a multicenter, randomized controlled trial of negative ion generation versus light-emitting diode phototherapy for seasonal affective disorder. Participants appropriate for the study are subjects with a DSM IV diagnosis of Major Depression, with seasonal pattern, winter type. Subjects were seen at Yale University,New Haven,CT University of British Columbia,Vancouver,BC Groningen University Hospital,Groningen, The Netherlands, Royal Ottawa Hospital, Ottawa,Ontario, McGill University, Montreal,Quebec, University Hospital,Saskatoon, Saskatchewan. The trial is 4 weeks in duration.

This trial has now been completed.

Eligibility

Ages Eligible for Study:	18 Years to 65 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria:

Subjects meet DSM-IV criteria for major depressive episodes with a seasonal pattern, winter type.

Exclusion Criteria:

Significant suicidal risk
Serious medical illness
Pregnancy
Other DSM-IV diagnoses
Taking mood altering medication
May not travel to a sunny destination during study

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00139997

Sponsors and Collaborators

Yale University

University of British Columbia

University Hospital

Royal Ottawa Hospital

McGill University

Royal University Hospital Foundation

Investigators

Principal Investigator:

Paul H. Desan, PhD, MD

Yale-New Haven Hospital

More Information

Publications indexed to this study:

Desan PH, Weinstein AJ, Michalak EE, Tam EM, Meesters Y, Ruiter MJ, Horn E, Telner J, Iskandar H, Boivin DB, Lam RW. A controlled trial of the Litebook light-emitting diode (LED) light therapy device for treatment of Seasonal Affective Disorder (SAD). BMC Psychiatry. 2007 Aug 7;7:38.

Study ID Numbers:	22,777, 22,777
Study First Received:	August 29, 2005
Last Updated:	August 29, 2005
ClinicalTrials.gov Identifier:	NCT00139997
Health Authority:	United States: Institutional Review Board

Keywords provided by Yale University:

Major Depression
Seasonal Affective Disorder (SAD)

Study placed in the following topic categories:

Seasonal Affective Disorder
Depression
Mental Disorders

Mood Disorders
Depressive Disorder, Major
Depressive Disorder

Additional relevant MeSH terms:

Pathologic Processes
Disease

ClinicalTrials.gov processed this record on January 16, 2009