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| Sponsored by: |
Ruhr University of Bochum |
|---|---|
| Information provided by: | Ruhr University of Bochum |
| ClinicalTrials.gov Identifier: | NCT00350116 |
Purpose
Objective: To test the efficacy and tolerability of a vitamin B12 cream for the treatment of chronic plaque psoriasis.
Design: Multicenter, double-blind, randomized, placebo-controlled trial.
| Condition | Intervention | Phase |
|---|---|---|
|
Chronic Plaque Psoriasis |
Drug: topical vitamin B12 |
Phase III |
| Study Type: | Interventional |
| Study Design: | Treatment, Randomized, Double-Blind, Placebo Control, Single Group Assignment, Safety/Efficacy Study |
| Official Title: | Topical Vitamin B12 in Chronic Plaque Psoriasis |
| Estimated Enrollment: | 48 |
| Study Start Date: | January 2001 |
| Estimated Study Completion Date: | December 2004 |
Objective: To test the efficacy and tolerability of a vitamin B12 cream for the treatment of chronic plaque psoriasis.
Design: Multicenter, double-blind, randomized, placebo-controlled trial. Setting: ambulatory patients in research or referral centers. Patients: Volunteer sample of 51 patients with chronic plaque psoriasis. Interventions: All Patients applied vitamin B12 cream twice daily for 8 weeks to one side of the body and placebo to the other.
Main outcome measures: Modified Psoriasis Area and Severity Index (PASI) at weeks 0, 2, 4, 6 and 8. Thickness and density of 3 references plaques determined by 20 MHz sonography. Assessment of efficiency and tolerability by patients and investigators.
Eligibility| Ages Eligible for Study: | 18 Years and older |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
Inclusion Criteria:
Exclusion Criteria:
Contacts and Locations| Germany | |
| Dep. Dermatology and Allergology, Ruhr-University Bochum | |
| Bochum, Germany, 44791 | |
| Principal Investigator: | Peter Altmeyer, Prof. Dr. | Ruhr University Bochum, Dep. Dermatology and Allergology |
More Information
| Study ID Numbers: | 1-Stucker |
| Study First Received: | July 6, 2006 |
| Last Updated: | July 6, 2006 |
| ClinicalTrials.gov Identifier: | NCT00350116 |
| Health Authority: | Germany: Federal Institute for Drugs and Medical Devices |
|
plaque psoriasis Vitamin B12 |
|
Skin Diseases Psoriasis Hydroxocobalamin Vitamin B 12 Skin Diseases, Papulosquamous |
|
Vitamin B Complex Hematinics Therapeutic Uses Growth Substances Vitamins |
Hematologic Agents Physiological Effects of Drugs Micronutrients Pharmacologic Actions |
