Autonomic Profiles in Pediatric Patients With Cyclic Vomiting Syndrome (CVS), Irritable Bowel Syndrome (IBS),Postural Orthostatic Tachycardia Syndrome (POTS), Functional Abdominal Pain (FAP) or Chronic Nausea

This study is ongoing, but not recruiting participants.

Sponsors and Collaborators:	Medical College of Wisconsin Children's Hospital and Health System Foundation, Wisconsin
Information provided by:	Medical College of Wisconsin
ClinicalTrials.gov Identifier:	NCT00728026

Purpose

Retrospectively review the charts of all children who had heart rate variability, deep breathing test, valsalva maneuver, tilt table test, thermoregulatory sweat testing, quantitative sudomotor axon reflex test (QSART) completed and were cared for at Children's Hospital of Wisconsin.

Condition
Vomiting Syndrome Irritable Bowel Syndrome Postural Orthostatic Tachycardia Syndrome Abdominal Pain Chronic Nausea

Genetics Home Reference related topics: Brugada syndrome short QT syndrome

MedlinePlus related topics: Abdominal Pain Nausea and Vomiting Sweat

U.S. FDA Resources

Study Type:	Observational
Study Design:	Case-Only, Retrospective
Official Title:	Autonomic Profiles in Pediatric Patients With Cyclic Vomiting Syndrome, Irritable Bowel Syndrome, Postural Orthostatic Tachycardia Syndrome, Functional Abdominal Pain or Chronic Nausea

Further study details as provided by Medical College of Wisconsin:

Primary Outcome Measures:

To gather preliminary data to characterize autonomic function in children and adolescents with functional gastrointestinal disorders. [ Time Frame: One year ] [ Designated as safety issue: No ]

Biospecimen Retention: None Retained

Biospecimen Description:

Estimated Enrollment:	50
Study Start Date:	June 2008
Estimated Study Completion Date:	June 2009

Groups/Cohorts
1 Cyclic Vomiting Syndrome
2 Irritable Bowel Syndrome
3 Postural Orthostatic Tachycardia Syndrome
4 Functional Abdominal Pain
5 Chronic Nausea

Eligibility

Ages Eligible for Study:	5 Years to 18 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No
Sampling Method:	Non-Probability Sample

Study Population

Diagnosis of either: Cyclic Vomiting Syndrome (CVS), Irritable Bowel Syndrome (IBS), Chronic nausea, Postural Orthostatic Tachycardia Syndrome (POTS), Functional Abdominal Pain (FAP)

Criteria

Inclusion Criteria:

Outpatient services

Exclusion Criteria:

Inpatient services

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00728026

Locations

United States, Wisconsin
Children's Hospital of Wisconsin
Milwaukee, Wisconsin, United States, 53226

Sponsors and Collaborators

Medical College of Wisconsin

Children's Hospital and Health System Foundation, Wisconsin

Investigators

Principal Investigator:

B UK Li

Medical College of Wiconsin

More Information

Responsible Party:	Medical College of Wisconsin ( B Li )
Study ID Numbers:	08/112, GC 680
Study First Received:	July 31, 2008
Last Updated:	August 4, 2008
ClinicalTrials.gov Identifier:	NCT00728026
Health Authority:	United States: Institutional Review Board

Keywords provided by Medical College of Wisconsin:

Chart must reveal the following procedures:
Heart rate variability,
Deep Breathing Test,
Valsalva maneuver,
Table test,

Thermoregulatory Sweat Testing,
Quantitative Sudomotor Axon Reflex Test (QSART),
Vital signs,
postural changes in heart rate and blood pressure,
composite autonomic score

Study placed in the following topic categories:

Heart Diseases
Vomiting
Signs and Symptoms, Digestive
Abdominal Pain
Gastrointestinal Diseases
Tachycardia
Colonic Diseases
Cyclic vomiting syndrome
Pain

Intestinal Diseases
Marijuana Abuse
Signs and Symptoms
Digestive System Diseases
Irritable Bowel Syndrome
Nausea
Postural orthostatic tachycardia syndrome
Colonic Diseases, Functional
Arrhythmias, Cardiac

Additional relevant MeSH terms:

Pathologic Processes
Disease
Syndrome
Cardiovascular Diseases

ClinicalTrials.gov processed this record on January 13, 2009