Physical Biochemistry: Thermodynamic and hydrodynamic properties of macromolecules and multi-component mixtures in solution, reversible interactions of biological macromolecules, reaction kinetics, reaction/diffusion problems in the gravitational field and at surfaces
Protein Structure/Function: Multi-protein complexes, membrane proteins in detergent solution, self-assembling and filamenting proteins, structural and nonstructural viral proteins, interactions of immunological cell surface receptors, T-cell receptor, superantigens
Biophysical Methods and Instrumentation: Analytical ultracentrifugation, surface plasmon resonance and biosensors, photon correlation spectroscopy, microcalorimetry, circular dichroism, mass spectrometry
Theory and Modeling: Finite element modeling, inversion of integral equations, regularization, maximum entropy methods, global modeling
Biotechnology Applications: Flow and detection principles in affinity biosensors; small volume biosensing from biological fluids, characterization of therapeutic antibodies; drug delivery particles
