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Types of Insulin

Each type of insulin has an onset, a peak, and a duration time.

The onset is how soon the insulin starts to lower your blood glucose after you take it.

The peak is the time the insulin is working the hardest to lower your blood glucose.

The duration is how long the insulin lasts—the length of time it keeps lowering your blood glucose.

The times shown in the chart are estimates. Your onset, peak, and duration times may be different. You’ll work with your health care team to come up with an insulin plan that works best for you.

Type of Insulin Brand Name Generic Name Onset Peak Duration
Rapid-acting  __ NovoLog  __ Insulin aspart 15 minutes 30 to 90 minutes 3 to 5 hours
 __ Apidra  __ Insulin glulisine 15 minutes 30 to 90 minutes 3 to 5 hours
 __ Humalog  __ Insulin lispro 15 minutes 30 to 90 minutes 3 to 5 hours
Short-acting  __ Humulin R  __ Regular (R) 30 to 60 minutes 2 to 4 hours 5 to 8 hours
 __ Novolin R
Intermediate-acting  __ Humulin N  __ NPH (N) 1 to 3 hours 8 hours 12 to 16 hours
 __ Novolin N
Long-acting  __ Levemir  __ Insulin detemir 1 hour Peakless 20 to 26 hours
 __ Lantus  __ Insulin glargine
Pre-mixed NPH
(intermediate-acting)
and regular (short-acting)
 __ Humulin 70/30
 __ Novolin 70/30
 __ 70% NPH and 30% regular 30 to 60 minutes Varies 10 to 16 hours
 __ Humulin 50/50  __ 50% NPH and 50% regular 30 to 60 minutes Varies 10 to 16 hours
Pre-mixed insulin lispro protamine suspension (intermediate-acting) and insulin lispro (rapid-acting  __ Humalog Mix 75/25  __ 75% insulin lispro protamine and 25% insulin lispro 10 to 15 minutes Varies 10 to 16 hours
 __ Humalog Mix 50/50  __ 50% insulin lispro protamine and 50% insulin lispro 10 to 15 minutes Varies 10 to 16 hours
Pre-mixed insulin aspart protamine suspension (intermediate-acting) and insulin aspart (rapid-acting)  __ NovoLog Mix 70/30  __ 70% insulin aspart protamine
and 30% insulin aspart
5 to 15 minutes Varies 10 to 16 hours

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