Endothelial and Left Ventricular Function in Preeclampsia

This study is ongoing, but not recruiting participants.

Sponsored by:	Norwegian University of Science and Technology
Information provided by:	Norwegian University of Science and Technology
ClinicalTrials.gov Identifier:	NCT00201500

Purpose

The purpose of this study is 1) to examine whether the endothelial function is impaired post partum in women with preeclampsia with preterm deliveries (<37 weeks) relative to women with preeclampsia with delivery at term, 2) to examine whether the left ventricular function is impaired in women with preeclampsia relative to healthy pregnant controls, 3) to examine whether there is a correlation between impairment of left ventricular function and impairment of endothelial function

Condition	Phase
Pre-Eclampsia	Phase I Phase II

U.S. FDA Resources

Study Type:	Observational
Study Design:	Case Control, Cross-Sectional
Official Title:	Endothelial and Left Ventricular Function in Preeclampsia, a Case Control Study

Further study details as provided by Norwegian University of Science and Technology:

Biospecimen Retention: Samples With DNA

Biospecimen Description:

Blood samples

Enrollment:	50
Study Start Date:	October 2004
Estimated Study Completion Date:	September 2009
Estimated Primary Completion Date:	September 2009 (Final data collection date for primary outcome measure)

Eligibility

Ages Eligible for Study:	18 Years to 40 Years
Genders Eligible for Study:	Female
Accepts Healthy Volunteers:	Yes
Sampling Method:	Probability Sample

Study Population

Local hospital and community midwives.

Criteria

Inclusion Criteria:

>18 years of age
Case: Clinical diagnosis of preeclampsia,
Control: Systolic BP <140 mmHg and diastolic BP <90 mmHg
No proteinuria

Exclusion Criteria:

Known hypertension or other cardiovascular disease
Serious mental illness
Smoking
Diabetes/gestational diabetes
Hypercholesterolemia

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00201500

Locations

Norway
NTNU
Trondheim, Norway, N-7491

Sponsors and Collaborators

Norwegian University of Science and Technology

Investigators

Study Chair:

Stig A Slørdahl, Professor

Norwegian University of Science and Technology

More Information

Responsible Party:	Norwegian University of Science and Technology ( Eva Veslemøy Tyldum )
Study ID Numbers:	PEETLV
Study First Received:	September 16, 2005
Last Updated:	January 30, 2008
ClinicalTrials.gov Identifier:	NCT00201500
Health Authority:	Norway: Norwegian Social Science Data Services

Study placed in the following topic categories:

Hypertension, Pregnancy-Induced
Pregnancy Complications
Eclampsia
Pregnancy toxemia /hypertension

Pre-Eclampsia
Preeclampsia
Hypertension

ClinicalTrials.gov processed this record on January 16, 2009