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Sponsors and Collaborators: |
Norwegian University of Science and Technology St. Olavs Hospital Dr. Dedichens Institute for Psychiatric Research, Oslo, Norway. GlaxoSmithKline |
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Information provided by: | Norwegian University of Science and Technology |
ClinicalTrials.gov Identifier: | NCT00201474 |
The purpose of the study is to investigate wether patients with brief depressive periodes together with other fluctuating psychiatric symptoms, have this condition due to epilepsy or an other organic brain disorder.
Condition |
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Acute Psychiatry Depressive Disorders |
Study Type: | Observational |
Study Design: | Psychosocial, Longitudinal, Convenience Sample, Prospective Study |
Official Title: | Signs of Organic Brain Dysfunction in Psychiatric Patients With Fluctuating Psychiatric Symptoms Including Brief Depressions Compared to Patients With a Major Depressive Episode. |
Estimated Enrollment: | 30 |
Study Start Date: | October 1998 |
Estimated Study Completion Date: | October 2004 |
A limited number of patients admitted to psychiatric acute wards or Psychiatric Intensive Care Units are admitted with a fluctuating array of psychiatric symptoms including brief depressive episodes. These patients do not fit into the present diagnostic systems due to short duration of affective symptoms and the flucuating arrays of other symptoms. Case histories indicate that these patients have psychiatric conditions due to epilepsy or organic brain dysfunctions.
In the study acutely admitted patients filling criteria for two recent DSM-4 axis 1 diagnoses (one is a brief depressive period) during the last two weeks are compared to age- and sex-matched patients acutely admitted with a major depressive disorder. The patients are rated with a number of rating scales at admittance, day 5, after two weeks and three months. EEG and QEEG are taken three times the first week. MRI, drug screening and blood screening of medication-consentrations are taken.
Ages Eligible for Study: | 18 Years and older |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
Exclusion Criteria:
Norway | |
Østmarka Psychiatric Department, St. Olavs Hospital | |
Trondheim, Norway, 7441 |
Study Chair: | Olav M Linaker, Professor | Norwegian University of Science and Technology |
Study ID Numbers: | AEV-98 |
Study First Received: | September 16, 2005 |
Last Updated: | September 16, 2005 |
ClinicalTrials.gov Identifier: | NCT00201474 |
Health Authority: | Norway: Norwegian Social Science Data Services |
brief depressive episodes affective disorders EEG and QEEG epilepsy organic brain disorders |
Depression Mental Disorders Epilepsy Mood Disorders |
Depressive Disorder Brain Diseases Behavioral Symptoms |
Pathologic Processes Disease |