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Sponsored by: |
Nantes University Hospital |
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Information provided by: | Nantes University Hospital |
ClinicalTrials.gov Identifier: | NCT00200564 |
The benefit of small doses of ketamine has been demonstrated for postoperative analgesia in adults but remains unproved in children. The investigators' purpose is to evaluate the effects of continuous intravenous small doses of ketamine versus placebo to improve the quality of postoperative analgesia in children (6 months to 6 years of age). Caudal anesthesia is performed for intraoperative analgesia and all children receive paracetamol, a non-steroidal anti-inflammatory and continuous intravenous nalbuphine.
Condition | Intervention | Phase |
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Postoperative Analgesia |
Drug: ketamine |
Phase IV |
Study Type: | Interventional |
Study Design: | Randomized, Single Blind, Placebo Control, Parallel Assignment |
Official Title: | Ketamine and Postoperative Analgesia in Children |
Estimated Enrollment: | 74 |
Study Start Date: | February 2004 |
Ages Eligible for Study: | 6 Months to 6 Years |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
Exclusion Criteria:
Contact: Véronique Bazin, MD | 00 33 2 40 08 35 47 | veronique.bazin@chu-nantes.fr |
France | |
Nantes University Hospital | Recruiting |
Nantes, France, 44093 | |
Contact: Véronique Bazin, MD 00 33 2 40 08 35 47 veronique.bazin@chu-nantes.fr |
Principal Investigator: | Véronique Bazin, MD | Nantes UH |
Study ID Numbers: | BRD/03/12-H |
Study First Received: | September 12, 2005 |
Last Updated: | October 22, 2007 |
ClinicalTrials.gov Identifier: | NCT00200564 |
Health Authority: | France: Afssaps - French Health Products Safety Agency |
Pediatrics ketamine postoperative analgesia nalbuphine Postoperative analgesia in children |
Excitatory Amino Acids Nalbuphine Ketamine |
Anesthetics, Intravenous Neurotransmitter Agents Molecular Mechanisms of Pharmacological Action Physiological Effects of Drugs Anesthetics Central Nervous System Depressants Excitatory Amino Acid Agents Anesthetics, Dissociative |
Pharmacologic Actions Sensory System Agents Anesthetics, General Therapeutic Uses Peripheral Nervous System Agents Analgesics Central Nervous System Agents Excitatory Amino Acid Antagonists |