Our Science – Dudley Website

Mark E. Dudley, Ph.D.

Surgery Branch Tumor Immunology Section Staff Scientist (Facility Head) Cell Production Facility CRC 3-5752 10 Center Drive Bethesda, MD 20892-1201 Phone:   301-496-1436 Fax:   Fax Number not listed E-Mail:   Mark_Dudley@nih.gov

Biography

Dr. Dudley Received a Bachelor of Science degree in Biology from the Massachusetts Institute of Technology in 1983 and a Ph.D. in Biological Sciences from Stanford University in 1988. He was a Jane Coffin-Childs research fellow at the University of Pennsylvania and a Cancer Research Institute/F.M.Kirby research fellow at the Jackson Laboratory prior to joining the Surgery Branch in 1996.

Research

The Cell Production Facility serves as a conduit between the Surgery Branch basic research laboratories and the patient clinics. Our mandate is to translate new research findings into successful gene therapy and cell based treatments for patients with cancer. Current efforts focus on clinical scale platforms for lymphocyte cell culture including closed bioreactors, retroviral and lentiviral gene therapy vectors, and artificial antigen presenting cells. These systems are being developed in the context of ongoing clinical trials to treat patients with advanced melanoma and other cancers.

This page was last updated on 9/9/2008.