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Interpersonal Psychotherapy for Depressed Adolescents and Parents
This study is currently recruiting participants.
Verified by New York State Psychiatric Institute, April 2008
Sponsors and Collaborators: New York State Psychiatric Institute
Columbia University
Information provided by: New York State Psychiatric Institute
ClinicalTrials.gov Identifier: NCT00619411
  Purpose

The purpose of this study is to examine the feasibility and acceptability of an adaptation of Interpersonal Psychotherapy for Depressed Adolescents (IPT-A) that includes greater and more structured involvement of the parents in the treatment.


Condition Intervention Phase
Major Depression
Dysthymic Disorder
Adjustment Disorders
Depressive Disorder Not Otherwise Specified
Behavioral: Interpersonal Therapy for Depressed Adolescents & Parents
Phase I

MedlinePlus related topics: Depression
U.S. FDA Resources
Study Type: Interventional
Study Design: Treatment, Non-Randomized, Open Label, Single Group Assignment
Official Title: An Open Clinical Trial of Interpersonal Psychotherapy for Depressed Adolescents and Parents

Further study details as provided by New York State Psychiatric Institute:

Primary Outcome Measures:
  • Clinical Global Improvement (CGI), Hamilton Rating Scale for Depression (HRSD), Center for Epidemiological Studies - Depression Scale (CES-D)

Secondary Outcome Measures:
  • Global Assessment Scale for Children (C-GAS), Social Adjustment Scale - Self-report (SAS-SR), Conflict Behavior Questionnaire (CBQ-20), Observational assessment of parent-adolescent communication

Study Start Date: November 2007
Arms Assigned Interventions
I: Experimental Behavioral: Interpersonal Therapy for Depressed Adolescents & Parents

Detailed Description:

Adolescent depression is a significant public health problem, and it increases the risk of poor psychosocial outcomes in adolescence and adulthood. Interpersonal Psychotherapy for Depressed Adolescents (IPT-A) has been found to be an effective treatment for reducing adolescents' depressive symptoms and improving their global and social functioning. The purpose of the current study is to examine the feasibility and acceptability of IPT-A when it is delivered with greater and more structured involvement of the parents in the treatment.

Participants will receive 15 weeks of Interpersonal Psychotherapy for Depressed Adolescents and Parents (IPT-AP). Eight the therapy sessions are conducted with the adolescent individually, two are with the parent(s) individually, and five are conducted with the adolescent and parent(s) together. At the end of the 15 weeks, participants who have demonstrated at least a 50% reduction in depressive symptoms will participate in three booster sessions delivered on a monthly basis. All participants will be assessed at baseline, week 5, week 10, week 15 (post-treatment), and 3 months post-treatment to measure depressive symptoms, global and social functioning, and attitudes toward treatment.

  Eligibility

Ages Eligible for Study:   12 Years to 18 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Meets diagnostic criteria for major depression, dysthymic disorder, depressive disorder not otherwise specified, or adjustment disorder with depressed mood
  • Score between 10 and 28 on the HRSD
  • Score of 65 or less on the C-GAS
  • English-speaking adolescent
  • Parental or legal guardian consent to participate

Exclusion Criteria:

  • Actively suicidal
  • Score greater than 28 on the HRSD
  • Mentally retarded
  • Meets diagnostic criteria for current substance abuse, schizophrenia, bipolar disorder, psychosis, conduct disorder, or eating disorder
  • Currently in active treatment for depression
  • Taking antidepressant medication at the time of baseline assessment
  • Medical illness likely to complicate or interfere with treatment
  • Victim of ongoing or previously undisclosed child abuse
  • Parent psychiatrically hospitalized within the past 3 months
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00619411

Contacts
Contact: Meredith Gunlicks, Ph.D. 212-543-5812 Gunlickm@childpsych.columbia.edu
Contact: Laura Mufson, Ph.D. 212-543-5561 MufsonL@childpsych.columbia.edu

Locations
United States, New York
Columbia University/New York State Psychiatric Institute Recruiting
New York, New York, United States, 10032
Contact: Meredith Gunlicks, Ph.D.     212-543-5812     Gunlickm@childpsych.columbia.edu    
Principal Investigator: Meredith Gunlicks, Ph.D.            
Sponsors and Collaborators
New York State Psychiatric Institute
Columbia University
Investigators
Principal Investigator: Meredith Gunlicks, Ph.D. Columbia University/New York State Psychiatric Institute
  More Information

Responsible Party: Columbia University/New York State Psychiatric Institute ( Meredith Gunlicks, Ph.D. )
Study ID Numbers: 5549
Study First Received: February 11, 2008
Last Updated: April 30, 2008
ClinicalTrials.gov Identifier: NCT00619411  
Health Authority: United States: Institutional Review Board

Keywords provided by New York State Psychiatric Institute:
Major Depression
Dysthymic Disorder
Adjustment Disorder
With Depressed Mood
Depressive
Disorder Not
Otherwise
Specified
Adolescent
Psychotherapy

Study placed in the following topic categories:
Adjustment Disorders
Depression
Mental Disorders
Mood Disorders
Dysthymic Disorder
Depressive Disorder, Major
Depressive Disorder
Behavioral Symptoms

Additional relevant MeSH terms:
Pathologic Processes
Disease

ClinicalTrials.gov processed this record on January 16, 2009