Does Metabolic Syndrome Exist in Anorexia Nervosa?

This study has been completed.

Sponsored by:	National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Information provided by:	National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
ClinicalTrials.gov Identifier:	NCT00271921

Purpose

The purpose of this study is to examine whether body fat distribution changes that occur with weight gain in women recovering from anorexia nervosa are transient or persistent, and if they are associated with other features of Metabolic Syndrome.

Condition	Intervention
Anorexia Nervosa Metabolic Syndrome	Behavioral: Calorie controlled diet

U.S. FDA Resources

Study Type:	Observational
Study Design:	Prospective
Official Title:	Does Metabolic Syndrome Exist in Anorexia Nervosa?

Further study details as provided by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK):

Estimated Enrollment:	50
Study Start Date:	September 2005
Study Completion Date:	June 2007
Primary Completion Date:	June 2007 (Final data collection date for primary outcome measure)

Eligibility

Ages Eligible for Study:	18 Years to 40 Years
Genders Eligible for Study:	Female
Accepts Healthy Volunteers:	Yes

Criteria

Inclusion Criteria:

DSM-IV diagnosis of Anorexia Nervosa (except amenorrhea) (restricting or binge eating/purging subtype)
Female
Age 18-40
Medically stable
Participation in inpatient or daypatient treatment sufficient to restore patient to a BMI of at least 19.5kg/m²

Exclusion Criteria:

Additional Major Axis I disorder (including substance abuse or dependence
On daily prescription medication (including oral contraceptives)
History of suicide attempt or other self-injurious behavior within the previous 6 months
Significant current or past medical illness,including diabetes mellitus, heart disease
Indwelling metallic object (e.g., pacemaker,pump), non-removable metal jewelry or recent metallic ink tattoo

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00271921

Locations

United States, New York
New York State Psychiatric Institute/Columbia University
New York, New York, United States, 10032
St. Luke's Roosevelt Hosptial Center
New York, New York, United States, 10025

Sponsors and Collaborators

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Investigators

Principal Investigator:	Laurel Mayer, MD	New York State Psychiatric Institute/Columbia University
Principal Investigator:	Henry Ginsberg, MD	Columbia University

More Information

Study ID Numbers:	DK66033
Study First Received:	December 29, 2005
Last Updated:	January 8, 2008
ClinicalTrials.gov Identifier:	NCT00271921
Health Authority:	United States: Federal Government

Keywords provided by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK):

eating disorders
anorexia nervosa
body fat distribution
metabolic syndrome
visceral adipose tissue

Study placed in the following topic categories:

Signs and Symptoms
Signs and Symptoms, Digestive
Mental Disorders

Anorexia
Anorexia Nervosa
Eating Disorders

Additional relevant MeSH terms:

Pathologic Processes
Disease
Syndrome

ClinicalTrials.gov processed this record on January 16, 2009