NT-proBNP for Evaluation of the Dyspneic Patient in the Emergency Room and the Medical Ward - Full Text View

Sponsored by:	Hillel Yaffe Medical Center
Information provided by:	Hillel Yaffe Medical Center
ClinicalTrials.gov Identifier:	NCT00271128

Purpose

The proposed study intends to evaluate the impact of the NT-proBNP assay on the diagnosis of heart failure in patients with dyspnea of unknown etiology presenting to the emergency room and admitted to the medical wards.

Condition
Shortness of Breath Acute Exacerbation

MedlinePlus related topics: Breathing Problems Heart Failure

U.S. FDA Resources

Study Type:	Observational
Study Design:	Prospective
Official Title:	NT-proBNP for Evaluation of the Dyspneic Patient in the Emergency Room and the Medical Ward (BNP4EVER)

Further study details as provided by Hillel Yaffe Medical Center:

Estimated Enrollment:	500
Study Start Date:	October 2005
Estimated Study Completion Date:	September 2007

Detailed Description:

The proposed study intends to evaluate the impact of the NT-proBNP assay on the diagnosis of heart failure in patients with dyspnea of unknown etiology presenting to the emergency room and admitted to the medical wards.

Patients will be consented and randomized to open or blinded NT-proBNP test performed within 90 minutes in a venous blood sample.

Evaluation of the ER diagnosis and final discharge diagnosis in admitted patients will be carried out in light of the NT-proBNP results.

Eligibility

Ages Eligible for Study:	18 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria:

Acute shortness of breath of unknown etiology as presentation to the emergency room
Possible acute exacerbation of known heart failure

Exclusion Criteria:

None -

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00271128

Locations

Israel
Hillel Yaffe Medical Center
Hadera, Israel

Sponsors and Collaborators

Hillel Yaffe Medical Center

Investigators

Principal Investigator:

Simcha R Meisel, MD MSc

Hillel Yaffe Medical Center

More Information

Study ID Numbers:	hymc34/2005
Study First Received:	December 29, 2005
Last Updated:	March 19, 2008
ClinicalTrials.gov Identifier:	NCT00271128
Health Authority:	Israel: Israeli Health Ministry Pharmaceutical Administration

Keywords provided by Hillel Yaffe Medical Center:

NT-proBNP
Heart failure
Dyspnea

Study placed in the following topic categories:

Signs and Symptoms
Heart Failure
Respiratory Tract Diseases
Respiration Disorders

Signs and Symptoms, Respiratory
Emergencies
Dyspnea

Additional relevant MeSH terms:

Disease Attributes
Pathologic Processes

ClinicalTrials.gov processed this record on January 16, 2009