Cancer Control Research
5R01CA087477-03
Connolly, Gregory N.
DESIGN AND CHARACTERIZATION OF CIGARETTES
Abstract
DESCRIPTION: (Applicant's Description)
The long term objective of this project is to advance scientific understanding
about the design and function of tobacco products through the acquisition,
analysis and reporting of internal tobacco industry documents held in the
Minnesota and other court depositories. Particular attention will be paid to
the use of additives and the design of low yield cigarettes. The specific aims
of this project include understanding how changes in cigarette design
contribute to youth smoking and nicotine dependence. Another aim is to
determine how cigarettes are designed to reduce non-smokers' perception of
second hand smoke. The project also hopes to improve scientific knowledge
about the toxic and addictive properties of cigarettes by reviewing tobacco
industry research on smoker behavior, changes in toxic constituents in
mainstream and side stream smoke and changes in nicotine delivery over time.
This project is relevant to national health policy. The Food and Drug
Administration has declared tobacco products to be drug delivery devices and
other govemments have proposed regulating tobacco products as drugs to reduce
death and diseases associated with their use. This project will provide
important scientific infonnation for the better characterization of tobacco
product perfonnance and such characterization is essential to tobacco product
regulation. The project will electronically access documents from the
Minnesota and other depositories for selected topic areas. Relevant documents
will be indexed using a standard thesaurus and placed both on the internet as
well as searchable CD roms and made available to policy makers and the
scientific community. Documents will be analyzed and scientific reports will
be written on tobacco product design, regulation and characterization.
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