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| Sponsored by: |
Samsung Medical Center |
|---|---|
| Information provided by: | Samsung Medical Center |
| ClinicalTrials.gov Identifier: | NCT00516230 |
Purpose
Correct identification of Lynch syndrome at the time of colorectal cancer presentation is important. We aim to find best ways to screen patients with colorectal cancer in Korea.
| Condition |
|---|
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Colonic Neoplasms |
| Study Type: | Observational |
| Study Design: | Screening, Longitudinal, Defined Population, Prospective Study |
| Official Title: | Establishing Effective Screening Methods for Diagnosing Hereditary Nonpolypoisis Colorectal Cancer |
| Estimated Enrollment: | 200 |
| Study Start Date: | January 2006 |
| Estimated Study Completion Date: | December 2011 |
Patients with newly diagnoised colorectal cancer will be eligible. They will undergo detailed history taking including family history, and molecular stuidies including microsatellite instability test and immunohistochemistry for DNA mismatch repair protein with pre-selection. Any abnormal finding in molecular stuides will be offered genetic testing (after testing methylation status for patients with abnormalities in MLH1).
Eligibility| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
Inclusion Criteria:
Exclusion Criteria:
Contacts and Locations| Contact: Dong Kyung Chang, M.D. Ph.D | +82-2-3410-3409 | dkchang@skku.edu |
| Contact: Tae Kuen Kim | +82-2-3410-2975 | tggo.kim@samsung.com |
| Korea, Republic of, Gangnam-gu | |
| Samsung Medical Center | Recruiting |
| Seoul, Gangnam-gu, Korea, Republic of, 135-710 | |
| Contact: Tae Kyun Kim +82-2-3410-2975 tggo.kim@samsung.com | |
| Principal Investigator: | Dong Kyung Chang, M.D. Ph.D | Division of Gastroenterology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine |
More Information
| Study ID Numbers: | SMC-2007-04-080 |
| Study First Received: | August 13, 2007 |
| Last Updated: | August 13, 2007 |
| ClinicalTrials.gov Identifier: | NCT00516230 |
| Health Authority: | South Korea: Institutional Review Board |
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Colonic Neoplasms Lynch syndrome |
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Digestive System Neoplasms Gastrointestinal Diseases Colonic Diseases Hereditary nonpolyposis colon cancer Intestinal Diseases Rectal Diseases Intestinal Neoplasms |
Digestive System Diseases Colorectal Neoplasms, Hereditary Nonpolyposis Colorectal cancer, hereditary nonpolyposis, type 1 Gastrointestinal Neoplasms Colonic Neoplasms Colorectal Neoplasms |
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Neoplasms Neoplasms by Site |
