Non-Prescription Versus Prescription Topical Treatments Versus no Treatment in the Control of Sweating - Full Text View

Sponsored by:	Northwestern University
Information provided by:	Northwestern University
ClinicalTrials.gov Identifier:	NCT00509886

Purpose

The purpose of this study is to assess the effectiveness of the prescription treatment compared to the non-prescription treatment. It is hypothesized that the prescription treatment will have a significantly greater effect than the non-prescription treatment on decreasing excess sweating.

Condition	Intervention
Hyperhidrosis Excess Sweating	Drug: Drysol Drug: Drioff

MedlinePlus related topics: Over-the-Counter Medicines Sweat

Drug Information available for: Chlorides Aluminum

U.S. FDA Resources

Study Type:	Interventional
Study Design:	Prevention, Randomized, Double Blind (Subject, Investigator), Active Control, Single Group Assignment, Efficacy Study
Official Title:	Non-Prescription Versus Prescription Topical Treatments Versus no Treatment in the Control of Sweating

Further study details as provided by Northwestern University:

Primary Outcome Measures:

Gravimetric analysis [ Time Frame: 3 hours ] [ Designated as safety issue: No ]

Secondary Outcome Measures:

Subject sweat assessment [ Time Frame: 3 hours ] [ Designated as safety issue: No ]
HDSS [ Time Frame: 3 hours ] [ Designated as safety issue: No ]

Enrollment:	24
Study Start Date:	June 2007
Study Completion Date:	April 2008
Primary Completion Date:	September 2007 (Final data collection date for primary outcome measure)

Arms	Assigned Interventions
1: Experimental ARMs were randomized. One side of the body received treatment with one antiperspirant and the contralateral side with a different antiperspirant.	Drug: Drysol 20% aluminum chloride hexahydrate
2: Experimental ARMs were randomized. One side of the body received treatment with one antiperspirant and the contralateral side with a different antiperspirant.	Drug: Drioff 1% aluminum acetate

Detailed Description:

The objective of this study is to assess the effectiveness of the prescription treatment compared to the non-prescription treatment. It is hypothesized that the prescription treatment will have a significantly greater effect than the non-prescription treatment on decreasing excess sweating.

Eligibility

Ages Eligible for Study:	21 Years to 30 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	Yes

Criteria

Inclusion Criteria:

age 21-30 years
males and females
The subjects are in good health.
The subjects have willingness and the ability to understand and provide informed consent for participation in the study.

Exclusion Criteria:

Subjects with primary hyperhidrosis
Subjects who are unable to withstand prolonged heat exposure or who have self-reported history of cardiovascular or respiratory disorders.
Subjects who are unable to give informed consent.
Subjects with mental illness.
Subjects who are pregnant or nursing.
Subjects with systemic or local skin disease and/or infection that may interfere with the conduct of the study.

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00509886

Locations

United States, Illinois
Northwestern University Dermatology
Chicago, Illinois, United States, 60611
Northwestern University Dermatology
Chicago, Illinois, United States, 60611

Sponsors and Collaborators

Northwestern University

Investigators

Principal Investigator:	Murad Alam, MD	Northwestern University dermatology
Study Chair:	Jillian A Havey	Northwestern University Feinberg School of Medicine
Study Director:	Dennis West, PhD	Northwestern University dermatology
Study Director:	Sara Ortiz	Northwestern University dermatology
Study Director:	Nicolle Martin, MD	Northwestern University Dermatology

More Information

Responsible Party:	Northwestern University Dermatology department ( Murad Alam, MD )
Study ID Numbers:	STU00000722
Study First Received:	July 31, 2007
Last Updated:	April 18, 2008
ClinicalTrials.gov Identifier:	NCT00509886
Health Authority:	United States: Institutional Review Board

Study placed in the following topic categories:

Skin Diseases
Hyperhidrosis

Additional relevant MeSH terms:

Sweat Gland Diseases

ClinicalTrials.gov processed this record on January 16, 2009