National Cancer Institute
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Epidemiology and Genetics Research Branch
Cancer Control and Population Sciences


NCI logo  Epidemiology and Genetics Research Program
Division of Cancer Control and Population Sciences
January 9, 2007

EGRP NEWS FLASH
From the Epidemiology and Genetics Research Program
Division of Cancer Control and Population Sciences
National Cancer Institute


Program Announcement Reissued on Exfoliated Cells, Bioactive Food Components, and Cancer

The Program Announcement (PA) Exfoliated Cells, Bioactive Food Components, and Cancer (PA-07-207) requesting applications for new Research Project Grants (R01) has been reissued.  This EGRP-sponsored announcement invites researchers to evaluate the use of exfoliated cells to monitor the physiological effects of dietary bioactive food components associated with cancer prevention. The aim is to encourage interdisciplinary collaborations between scientists using exfoliated cells in research and those conducting nutrition research related to cancer prevention. This research will help determine the use of exfoliated cells as a model system to monitor both the absorption and retention of bioactive food components and the concomitant alterations in genomic and epigenetic events that occur in intact cells.

  • This PA appears in the NIH Guide for Grants and Contracts (PA-07-207).

Two separate funding announcements of identical scientific scope inviting small and exploratory grant applications were announced in April 2006: 

  • PA-06-360 to solicit applications under the Small Grant (R03) mechanism
  • PA-06-359 to solicit applications under the Exploratory/Developmental Grant (R21) mechanism

Direct scientific questions about these PAs to EGRP's Virginia (Ginny) Hartmuller, Ph.D., R.D.; e-mail:  hartmulv@mail.nih.gov.


Four New Papers Focus on Big Science, Evolution of Epidemiology

Four new papers that focus on big science and the evolution of epidemiology have been published by EGRP grantees and NCI staff. The papers appear in the January 2007 issue of Epidemiology: 

  • The Emergence of Networks in Human Genome Epidemiology: Challenges and Opportunities by EGRP’s Daniela Seminara, Ph.D., M.P.H.; Debbie Winn, Ph.D.; and others.

    PubMed Reference:
    Seminara D, Khoury MJ, O'Brien TR, Manolio T, Gwinn ML, Little J, Higgins JP, Bernstein JL, Boffetta P, Bondy M, Bray MS, Brenchley PE, Buffler PA, Casas JP, Chokkalingam AP, Danesh J, Davey Smith G, Dolan S, Duncan R, Gruis NA, Hashibe M, Hunter D, Jarvelin MR, Malmer B, Maraganore DM, Newton-Bishop JA, Riboli E, Salanti G, Taioli E, Timpson N, Uitterlinden AG, Vineis P, Wareham N, Winn DM, Zimmern R, Ioannidis JP; Human Genome Epidemiology Network; the Network of Investigator Networks. The emergence of networks in human genome epidemiology: challenges and opportunities. Epidemiology. 2007 Jan;18(1):1-8.

  • "Big" Science and the Little Guy by EGRP grantee Roberta Ness, M.D., M.P.H.

    PubMed Reference:
    Ness RB. “Big” science and the little guy. Epidemiology. 2007 Jan;18(1):9-12.

  • The Evolution of Epidemiologic Research: From Cottage Industry to ‘Big’ Science by Robert Hoover, Director of the Epidemiology and Biostatistics Program at the NCI’s DCEG.  

    PubMed Reference:
    Hoover RN. The evolution of epidemiologic research: from cottage industry to "big" science. Epidemiology. 2007 Jan;18(1):13-7.

  • How Big Is Big Enough for Epidemiology? by EGRP grantee George Kaplan, Ph.D.  

    PubMed Reference:
    Kaplan GA. How big is big enough for epidemiology? Epidemiology. 2007 Jan;18(1):18-20.


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Last modified:
24 May 2007
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