Inclusion Criteria:

• Participants who are able to differentiate urinary incontinence episodes associated with urgency from urinary incontinence episodes not associated with urgency
• During the 7 day baseline period have 21 to 60 urge urinary incontinence (Urge-UI) episodes, a greater number of Urge-UI episodes than urinary incontinence not associated with urge, and an average of 10 or more voids per 24 hours
• Are in good general health as determined by medical history, physical examination (general, genital, pelvic, and rectal), laboratory tests and urinalysis
• If taking antihypertension medication, must be on a stable dose
• And if of child-bearing potential, practicing an acceptable method of birth control, and must have a negative pregnancy test at Visit 2 and Visit 3

Exclusion Criteria:

• Participants with known, treatable genitourinary conditions (identified on history or on examination) that may cause incontinence (e.g., urinary tract infection, interstitial cystitis, urinary tract obstruction, urethral diverticulum, bladder tumor, bladder stone)
• Have given birth or have had pelvic, vaginal or bladder surgery less than 6 months before study enrollment
• With a second post-void residual urine volume > 150 mL at the time of screening (determined by abdominal ultrasound)
• With significant medical problems or other organ abnormality that places them at risk from participating in the study or at a significant risk of developing complete urinary retention
• With significant impairment of the liver or kidneys as determined by laboratory assessments or hematuria (red blood cells in microscopic urinalysis)