Effect of Whole Body Vibration on Bone and Fall Related Parameters - Full Text View

Sponsors and Collaborators:	University of Erlangen-Nürnberg Institute of Biometrie and Medical Statistics Netzwerk-Knochengesundheit Siemens-Betriebskrankenkasse
Information provided by:	University of Erlangen-Nürnberg
ClinicalTrials.gov Identifier:	NCT00292916

Purpose

The effect of whole body vibration (WBV) on bone strength and fall frequency in older adults is still vague. Although there is some evidence that WBV may impact Bone Mineral Density in very frail elderly, there is a lack of data concerning the effect of WBV in community-living elderly woman. We hypothesize that WBV significantly affects bone parameters as assessed by DXA, QCT, US and bone markers with parallel positive changes of fall related risk factors (power, strength, balance, and reaction time). We further hypothesize that the effects of WBV were superior to conventional resistance exercise.

Condition	Intervention	Phase
Atrophy	Behavioral: whole body vibration Behavioral: resistance exercise Behavioral: "wellness"	Phase III

MedlinePlus related topics: Exercise and Physical Fitness Minerals

U.S. FDA Resources

Study Type:	Interventional
Study Design:	Prevention, Randomized, Single Blind, Active Control, Parallel Assignment, Safety/Efficacy Study
Official Title:	Effect of Whole Body Vibration on Bone and Fall Related Parameters - the Erlangen Longitudinal Vibration Study (ELVIS)

Further study details as provided by University of Erlangen-Nürnberg:

Primary Outcome Measures:

BMD after 6, 12 and 18 months
strength
power

Secondary Outcome Measures:

balance
bone markers

Estimated Enrollment:	150
Study Start Date:	January 2006
Estimated Study Completion Date:	July 2007

Eligibility

Ages Eligible for Study:	65 Years and older
Genders Eligible for Study:	Female
Accepts Healthy Volunteers:	Yes

Criteria

Inclusion Criteria:

community living elderly females >/=65 years
live expectation > 2 years

Exclusion Criteria:

secondary osteoporosis
CVD-events including stroke
participation in other studies
medication and illness affecting bone metabolism within the last 2 years
medication with impact on falls
low physical performance (<50 Watt during ergometry)
excessive alcohol-intake

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00292916

Locations

Germany
Institute of Medical Physics
Erlangen, Germany, 91052

Sponsors and Collaborators

University of Erlangen-Nürnberg

Institute of Biometrie and Medical Statistics

Netzwerk-Knochengesundheit

Siemens-Betriebskrankenkasse

Investigators

Study Chair:

Willi A Kalender, PhD

University of Erlangen-Nürnberg

More Information

Publications:

Kemmler W, Engelke K, Baumann H, Beeskow C, von Stengel S, Weineck J, Kalender WA. Bone status in elite male runners. Eur J Appl Physiol. 2006 Jan;96(1):78-85. Epub 2005 Oct 26.

Engelke K, Kemmler W, Lauber D, Beeskow C, Pintag R, Kalender WA. Exercise maintains bone density at spine and hip EFOPS: a 3-year longitudinal study in early postmenopausal women. Osteoporos Int. 2006 Jan;17(1):133-42. Epub 2005 Aug 12.

Stengel SV, Kemmler W, Pintag R, Beeskow C, Weineck J, Lauber D, Kalender WA, Engelke K. Power training is more effective than strength training for maintaining bone mineral density in postmenopausal women. J Appl Physiol. 2005 Jul;99(1):181-8. Epub 2005 Mar 3.

Kemmler W, Weineck J, Kalender WA, Engelke K. The effect of habitual physical activity, non-athletic exercise, muscle strength, and VO2max on bone mineral density is rather low in early postmenopausal osteopenic women. J Musculoskelet Neuronal Interact. 2004 Sep;4(3):325-34.

Study ID Numbers:	D-ER-OFZ-200501-Vib
Study First Received:	February 15, 2006
Last Updated:	July 27, 2007
ClinicalTrials.gov Identifier:	NCT00292916
Health Authority:	Germany: Bayrisches Staatsministerium für Wissenschaft, Forschung und Kunst

Keywords provided by University of Erlangen-Nürnberg:

whole body vibration
exercise
elderly woman

Bone Mineral Density
falls
higher age

Study placed in the following topic categories:

Pathological Conditions, Anatomical
Atrophy

ClinicalTrials.gov processed this record on January 14, 2009