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Sponsors and Collaborators: |
The University of Texas Health Science Center at San Antonio DePuy Orthopaedics |
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Information provided by: | The University of Texas Health Science Center at San Antonio |
ClinicalTrials.gov Identifier: | NCT00156598 |
Other research studies have shown that the levels of metals in the blood are slightly increased after patients receive a total hip replacement. We want to learn whether these elevated levels are associated with any adverse effects. We hope this study will help us identify which type of patients have elevated levels of metal in their blood.
Condition |
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Osteoarthritis |
Study Type: | Observational |
Study Design: | Natural History, Cross-Sectional, Convenience Sample, Retrospective/Prospective Study |
Official Title: | Cobalt, Chromium and Titanium Serum Concentrations in Patients With Metal-on-Metal vs. Metal on Polyethylene Total Hip Replacements |
Estimated Enrollment: | 45 |
Study Start Date: | August 2004 |
Estimated Study Completion Date: | December 2007 |
It is suspected that the concentration of the metals chromium, cobalt and titanium in the blood will be higher in people with an all metal total hip prosthesis than in those with a plastic and metal prosthesis. To find out if this is true, we will test blood samples for the levels of metal in the blood and compare the values from 3 groups of people:
Ages Eligible for Study: | 18 Years and older |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | Yes |
Inclusion Criteria:
Group 1 - unilateral hip replacement with metal on metal prosthesis, well functioning.
Group 2 - loosening of plastic and metal prosthesis Group 3 - osteoarthritis of the hip and awaiting total hip replacement
Exclusion Criteria:
Contact: Pat Cathcart | (210) 567-0204 | cathcart@uthscsa.edu |
United States, Texas | |
UT Medicine- San Antonio (formerly UPG-DP clinic) | Recruiting |
San Antonio, Texas, United States, 78229 | |
Contact: Kathy Nelson 210-592-0180 | |
Sub-Investigator: Hussein Turki, MD |
Principal Investigator: | Lorence Trick, MD | University of Texas Health Science Center Department of Orthopaedics |
Study ID Numbers: | 045-0031-006 |
Study First Received: | September 7, 2005 |
Last Updated: | June 14, 2007 |
ClinicalTrials.gov Identifier: | NCT00156598 |
Health Authority: | United States: Institutional Review Board |
metal ion concentration |
Chromium Musculoskeletal Diseases Osteoarthritis Cobalt |
Joint Diseases Arthritis Rheumatic Diseases |