Engineering Altered Sensory Systems: Regulation of Gene Expression and Function in Mammalian Olfaction |
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| Launch in standalone player | |
| Air date: | Monday, February 10, 2003, 12:00:00 PM |
| Category: | Neuroscience |
| Description: | NIH Neuroscience Seminar
The mammalian olfactory system relies on a specialized signal transduction system and highly organized neuronal wiring to detect odorants with high sensitivity and specificity. Targeted manipulation of genetic components in this system have revealed important roles of the odorant receptor,the cyclic nucleotide-gated ion channel and tissue-specific transcription factors for neuronal development, axonal targeting, stimulus detection, and desensitization. Dr. Reed has been a pioneer in characterizing the molecular bases of olfaction. His current research addresses how the genes that encode odorant receptors are organized and how their expression is regulated. He uses mouse models engineered with altered expression of olfactory receptors to study the patterns of activity and neuronal connections in the brain More information by Randy Reed |
| Author: | Randall Reed, Ph.D., Johns Hopkins University |
| Runtime: | 60 minutes |
| Rights: | This is a work of the United States Government. No copyright exists on this material. It may be disseminated freely. |
| Download: | Download
Video How to download a Videocast |
| CIT File ID: | 10863 |
| CIT Live ID: | 1987 |
| Permanent link: | http://videocast.nih.gov/launch.asp?10863 |