Mechanisms of Signaling by Neuronal ApoE Receptors |
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| Launch in standalone player | |
| Air date: | Monday, January 27, 2003, 12:00:00 PM |
| Category: | Neuroscience |
| Description: | Apolipoprotein E is the only gene that has been unambiguously identified as a risk factor for late-onset Alzheimer’s Disease. The molecular mechanisms by which the e4 isoform of ApoE predisposes to the disease remains shrouded in mystery. Dr. Herz's laboratory investigates the biology of a family of ApoE receptors, also known as the LDL receptor gene family, and their functions in neurons and in other tissues. Their findings show that ApoE receptors are intrinsic components of classical signaling pathways, where they control brain development as well as the integrity of the vascular wall.
For more information, visit Joachim Herz The NIH Neuroscience Seminar Series features lectures and discussions with leading neuroscientists. |
| Author: | Joachim Herz, M.D., University of Texas |
| Runtime: | 70 minutes |
| Rights: | This is a work of the United States Government. No copyright exists on this material. It may be disseminated freely. |
| Download: | Download
Video How to download a Videocast |
| CIT File ID: | 10857 |
| CIT Live ID: | 1985 |
| Permanent link: | http://videocast.nih.gov/launch.asp?10857 |