Prediction of Medication Compliance

This study is currently recruiting participants.

Verified by University of Minnesota, June 2007

Sponsors and Collaborators:	University of Minnesota National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Information provided by:	University of Minnesota
ClinicalTrials.gov Identifier:	NCT00148187

Purpose

The purpose of this study is to quantitate pre-transplant medication compliance, dialysis compliance, and related psychological variables, and then examine their validity as predictors of post-transplant noncompliant behaviors and clinically relevant outcomes (acute rejection, graft loss, or death).

Hypothesis: Noncompliance with pre-transplant medication or with the dialysis prescription, and specific psychological variables predict similarly noncompliant behaviors after transplantation.

Condition
Kidney Transplantation

MedlinePlus related topics: Kidney Transplantation

U.S. FDA Resources

Study Type:	Observational
Study Design:	Natural History, Longitudinal, Convenience Sample, Prospective Study
Official Title:	Prediction of Medication Compliance Following Renal Transplantation

Further study details as provided by University of Minnesota:

Estimated Enrollment:	60
Study Start Date:	January 2003

Detailed Description:

This pilot study is intended to provide preliminary data about the feasibility of recruiting a cohort of subjects on hemodialysis and following them prospectively through the transplant procedure. The study will document patient adherence to medications and treatment, both before and after surgery. These preliminary data will permit appropriate design and power calculations for a future study assessing our ability to predict post-transplant compliance, based on pre-transplant behaviors.

Eligibility

Ages Eligible for Study:	18 Years to 70 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria:

Adult hemodialysis patients in renal transplant evaluation
Able to read test forms
Responsible for their own medications

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00148187

Contacts

Contact: Thomas E Nevins, MD

612-626-2922

nevin001@umn.edu

Locations

United States, Minnesota
University of Minnesota	Recruiting
Minneapolis, Minnesota, United States, 55455
Contact: Thomas E Nevins, MD 612-626-2922 nevin001@umn.edu

Sponsors and Collaborators

University of Minnesota

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Investigators

Principal Investigator:

Thomas E Nevins, MD

University of Minnesota

More Information

Study ID Numbers:	0202M17442, NIH - DK13083
Study First Received:	September 2, 2005
Last Updated:	July 16, 2007
ClinicalTrials.gov Identifier:	NCT00148187
Health Authority:	United States: Institutional Review Board

Keywords provided by University of Minnesota:

Medication adherence
Patient compliance
Kidney transplant

Organ rejection
Allograft loss
Drug monitoring

ClinicalTrials.gov processed this record on January 16, 2009