Tell CCR
"Tell CCR" about newly accepted/in press papers prior to online and print publication. Please include a copy of the manuscript in your e-mail to tellccr@mail.nih.gov
Questions may be directed to Donna Kerrigan
Our News - 2006 Scientific Advances from CCR
The twelve advances shown below were selected by CCR senior staff in response to a request from the NCI Office of Science Policy and Assessment (OSPA). OSPA will consider these advances for inclusion in the NCI¹s Annual Report and as Cancer Bulletin features.
Advances in Lymphoma Research - two submissions by Louis Staudt and co-workers:
A Loss-of-Function RNA Interference Screen for Molecular Targets in Cancer
Molecular Diagnosis of Burkitt's Lymphoma
Advances in Kidney Cancer Research - submission by W. Marston Linehan:
Folliculin Encoded by the BHD Gene Interacts with a Novel Binding Protein, FNIP1,and AMPK, and Is Involved in AMPK and mTOR Signaling
Advances in Regulation of Immune Response in Cancer – submission by Crystal Mackall:
Interleukin-2 and T Cell Depletion Expand Suppressive T Cells in Humans
Advances in Development of an AIDS Vaccine - submission by Marjorie Robert-Guroff:
Replication-Competent Ad-HIV Vaccine for AIDS
Advances in AIDS-related Kaposi¹s Sarcoma - submission by Robert Yarchoan:
Interleukin-12 (IL-12) Has Clinical Activity Against AIDS-related Kaposi¹s Sarcoma
Advances in Melanoma Therapy - submission by Steve Rosenberg:
New Method of Gene Therapy Alters Immune Cells for Treatment of Advanced Melanoma
Advances in Chromosome Biology and Genomic Instability - four submissions by Andre Nussenzweig and William Bonner:
Autophosphorylation at Serine 1987 Is Dispensable for Murine Atm Activation In Vivo
Changes in Chromatin Structure and Mobility in Living Cells at Sites of DNA Double-Strand Breaks
Role of Genomic instability and p53 in AID-induced c-myc-Igh Translocations
Investigator: Andre Nussenzweig
Ionizing Radiation Induces DNA Double-Strand Breaks in Bystander Primary Human Fibroblasts
Investigator: William Bonner
Basic Science Discovery of Mechanisms of Aging - submission by Tom Misteli:
Identification of a Novel Mechanism of Human Aging
Advances in HPV Research Identification of HPV Infection Inhibitor - submission by John Schiller:
Carrageenan Is a Potent Genital HPV Infection Inhibitor
Advance in Kidney Cancer - submission by J. Carl Barrett and Joseph Riss:
Cancer as Wounds That Do Not Heal: Differences and Similarities in Renal Cell Carcinoma and Renal Tissue
Advances in Immunology Research - submission by Jay Berzofsky:
Nonclassical (Type II) NKT Cells Are Regulators of Tumor Immunosurveillance and Allow Tumor Recurrence
Advances in Stem Cell Research - submissions by Steven Hou and Snorri Thorgeirsson:
The Drosophila Homologue of the Human Tumor Suppressor Gene BHD Interacts with the JAK-STAT and TGF-beta Signaling Pathways in Regulating Male Germline Stem Cell Maintenance
Investigator: Steven Hou
Cancer Stem Cells: Subtype of Human Hepatocellular Carcinoma Derived from Hepatic Progenitor Cells
Investigator: Snorri Thorgeirsson
