Rijavithi Viral PCR Arrays in CNS Infection Study - Full Text View

Rijavithi Viral PCR Arrays in CNS Infection Study (VIPAC)

This study is not yet open for participant recruitment.

Verified by Rajavithi Hospital, December 2008

Sponsors and Collaborators:	Rajavithi Hospital Rajavithi Biomolecular Research Center
Information provided by:	Rajavithi Hospital
ClinicalTrials.gov Identifier:	NCT00807378

Purpose

This study of neurotropic viral infection is the comprehensive investigation of CSF PCR arrays (Hybrydiaztion technique, real time PCR arrays of CSF ) in suspected cases of viral CNS infection in both AIDS and non AIDS patients.

Patients with clinical viral encephalitis and meningoencephalitis including all pateints with HIV/AIDS CSF and non AIDS will be banked and test for RNA and DNA viral sequence by Real time PCR arrays. Clinical data and final diagnosis will be used to analyse the result of this PCR arrays technique.

Condition	Intervention
CNS Viral Infection	Other: LUMBAR PUNCTURE

U.S. FDA Resources

Study Type:	Observational
Study Design:	Case-Only, Prospective
Official Title:	Cerebrospinal Fluid Polymerase Chain Reaction Arrays for Central Nervous System Neurotropic Viral Infection Study

Further study details as provided by Rajavithi Hospital:

Biospecimen Retention: Samples With DNA

Biospecimen Description:

CSF DNA/RNA virus

Estimated Enrollment:	200
Study Start Date:	January 2009
Estimated Primary Completion Date:	December 2009 (Final data collection date for primary outcome measure)

Groups/Cohorts	Assigned Interventions
1 AIDS PATIENTS	Other: LUMBAR PUNCTURE LUMBAR PUNCTURE FFOR CSF COLLECTION
2 NON-AIDS PATIENTS	Other: LUMBAR PUNCTURE LUMBAR PUNCTURE FFOR CSF COLLECTION

Eligibility

Ages Eligible for Study:	15 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No
Sampling Method:	Non-Probability Sample

Study Population

CNS VIRAL INFECTION AIDS/NON-AIDS

Criteria

Inclusion Criteria:

AGE MORE THAN 15 YRS
ABLE TO INFORM CONSENT BY THEMSELF OR THEIR PARENT
SUSPECTED CNS VIRAL INFECTION

Exclusion Criteria:

UNABLE/CONTRAINDICATED FOR LUMBAR PUNCTURE OR CSF COLLECTION
WITHDRAW CONSENT
SUSPECTED SEVERE OR VILURENT VIRAL INFECTION SUCH AS H5N1/SARS INFECTION

Contacts and Locations

No Contacts or Locations Provided

More Information

Responsible Party:	Rajavithi Biomolecular Research Center ( Piyathida Harnsomboonrana )
Study ID Numbers:	RH-CMR-004
Study First Received:	December 9, 2008
Last Updated:	December 9, 2008
ClinicalTrials.gov Identifier:	NCT00807378
Health Authority:	Thailand: Ministry of Public Health

Keywords provided by Rajavithi Hospital:

CNS viral infection
PCR
HYBRIDIZATION

Study placed in the following topic categories:

Virus Diseases
Central Nervous System Infections

Additional relevant MeSH terms:

Communicable Diseases
Infection

ClinicalTrials.gov processed this record on January 16, 2009