Examination of B Cell Responses in Human Blood

This study is ongoing, but not recruiting participants.

Sponsors and Collaborators:	Regenerative Medicine Network University of Leipzig
Information provided by:	Regenerative Medicine Network
ClinicalTrials.gov Identifier:	NCT00806845

Purpose

The aim of this study is the assessment B-cell immune responses in HIV-infected individuals.

Condition
HIV Infections

MedlinePlus related topics: AIDS

Study Type:	Observational
Study Design:	Cohort, Prospective
Official Title:	Gewinnung Humaner antikörperproduzierender Zellen Aus Dem Blut

Further study details as provided by Regenerative Medicine Network:

Primary Outcome Measures:

Antigen specific B-cell responses [ Time Frame: 18 months ] [ Designated as safety issue: No ]

Biospecimen Retention: Samples Without DNA

Biospecimen Description:

peripheral blood

Estimated Enrollment:	40
Study Start Date:	July 2008
Estimated Study Completion Date:	May 2011
Estimated Primary Completion Date:	December 2010 (Final data collection date for primary outcome measure)

Groups/Cohorts
HIV infected individuals HIV infected individuals with or without AIDS
Control HIV negative individuals

Detailed Description:

Groups of patients with different immune competencies will be examined. The impact of HIV infection on immune response will be assessed.

Eligibility

Study Population

HIV patients and controls attending specialised clinics, Germany

Criteria

Inclusion Criteria:

Exclusion Criteria:

- none

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00806845

Locations

Sponsors and Collaborators

Regenerative Medicine Network

University of Leipzig

Investigators

Study Director:

Christian Jassoy, MD

Universität Leipzig

More Information

Responsible Party:	Universität Leipzig ( Christian Jassoy MD )
Study ID Numbers:	RegMedNet-001
Study First Received:	December 10, 2008
Last Updated:	January 7, 2009
ClinicalTrials.gov Identifier:	NCT00806845
Health Authority:	Germany: Ethics Commission

Keywords provided by Regenerative Medicine Network:

HIV
B-lymphocyte

Study placed in the following topic categories:

Virus Diseases
Sexually Transmitted Diseases, Viral
HIV Infections
Sexually Transmitted Diseases

Acquired Immunodeficiency Syndrome
Retroviridae Infections
Immunologic Deficiency Syndromes

Additional relevant MeSH terms:

RNA Virus Infections
Slow Virus Diseases
Immune System Diseases
Lentivirus Infections
Infection

ClinicalTrials.gov processed this record on January 16, 2009