![]() |
Home
Search
Study Topics
Glossary
|
![]() |
![]() |
![]() |
|
![]() |
|
![]() |
|
![]() |
|
![]() |
![]() |
![]() |
|
![]() |
Sponsored by: |
Winthrop University Hospital |
---|---|
Information provided by: | Winthrop University Hospital |
ClinicalTrials.gov Identifier: | NCT00656929 |
Background: Vitamin D has been shown to be an important immune system regulator. Vitamin D insufficiency during the winter may cause increased susceptibility to infections, particularly viral upper respiratory tract infections (URIs).
Objective: To determine whether vitamin D supplementation during the winter season prevents or decreases URI symptoms in adults.
Methods: A randomized, double-blind, placebo-controlled trial was conducted in 162 adults. Participants were randomized to receive vitamin D3 50 mcg (2000 IU) daily or matching placebo for 12 weeks from December 2006 to March 2007. A biweekly questionnaire was used to record the incidence and severity of URI symptoms
Condition | Intervention |
---|---|
Viral Upper Respiratory Tract Infection |
Dietary Supplement: Vitamin D3 Other: Placebo |
Study Type: | Interventional |
Study Design: | Prevention, Randomized, Double Blind (Subject, Investigator), Placebo Control, Parallel Assignment, Efficacy Study |
Official Title: | A Randomized Controlled Trial of Vitamin D3 Supplementation for the Prevention of Viral Upper Respiratory Tract Infections |
Enrollment: | 167 |
Study Start Date: | December 2006 |
Study Completion Date: | June 2007 |
Primary Completion Date: | June 2007 (Final data collection date for primary outcome measure) |
Arms | Assigned Interventions |
---|---|
1: Active Comparator
Vitamin D3 50 mcg (2000 IU) daily
|
Dietary Supplement: Vitamin D3
Vitamin D3 (cholecalciferol) 50 mcg (2000 IU) daily x 3 months
|
2: Placebo Comparator
Placebo tablets
|
Other: Placebo
Placebo tablets
|
Ages Eligible for Study: | 18 Years to 80 Years |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | Yes |
Inclusion Criteria:
Exclusion Criteria:
Responsible Party: | Winthrop University Hospital ( John F. Aloia, M.D. ) |
Study ID Numbers: | WUH06034 |
Study First Received: | April 7, 2008 |
Last Updated: | April 10, 2008 |
ClinicalTrials.gov Identifier: | NCT00656929 |
Health Authority: | United States: Institutional Review Board |
Vitamin D Viral URI Influenza Colds |
Cholecalciferol Vitamin D Respiratory Tract Diseases |
Respiratory Tract Infections Ergocalciferols Influenza, Human |
Communicable Diseases Growth Substances Vitamins Physiological Effects of Drugs |
Bone Density Conservation Agents Micronutrients Infection Pharmacologic Actions |