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Your search term(s) "Interstitial Cystitis" returned 23 results.

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Interstitial Cystitis/Painful Bladder Syndrome. Bethesda, MD: National Kidney and Urologic Diseases Information Clearinghouse. 2008. 12 p.

This fact sheet describes interstitial cystitis (IC), a condition that results in recurring discomfort or pain in the bladder and the surrounding pelvic region. Symptoms may include an urgent need to urinate, a frequent need to urinate, or a combination of these symptoms. In recent years, scientists have started to use the term painful bladder syndrome (PBS) to describe cases with painful urinary symptoms that may not meet the strictest definition of IC. Written in a question-and-answer format, the fact sheet covers a definition of these urinary conditions; the causes of IC; diagnostic strategies, including urinalysis and urine culture, culture of prostate secretions, cystoscopy under anesthesia with bladder distention, and biopsy; treatments for IC and PBS, including bladder distention, bladder instillation, oral drugs, transcutaneous electrical nerve stimulations, diet, quitting smoking, exercise, bladder training, and surgery; and special concerns, including pregnancy and the psychosocial impact of coping with IC and PBS. The fact sheet concludes with a summary of research programs in this area, a list of suggested readings, a list of resource organizations for readers wanting additional information, and a brief description of the activities of the National Kidney and Urologic Diseases Information Clearinghouse. 3 figures.

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Interstitial Cystitis (Painful Bladder Syndrome). Washington, DC: National Women’s Health Information Center. 2007. 4 p.

This fact sheet answers common questions about interstitial cystitis (IC), a condition also called painful bladder syndrome. IC is defined as a chronic bladder problem that can cause pain and other symptoms. People with IC have an inflamed and irritated bladder that can lead to scarring and stiffening of the bladder, less bladder capacity, and bleeding in the bladder. IC can vary from relatively mild symptoms to severe cases that have an impact on the person’s quality of life. The fact sheet discusses the current research on the causes of IC, the symptoms and signs of the condition, diagnostic tests used to confirm the presence of IC, how diet affects IC, pregnancy in women with IC, and treatment options including bladder distention, bladder instillation, oral medicines, transcutaneous electrical nerve stimulation (TENS), self-help strategies, and surgery. A final section lists contact information for three resource organizations through which readers can get additional information: the National Kidney and Urologic Diseases Information Clearinghouse at 1–800–891–5390 or www.kidney.niddk.nih.gov, the Interstitial Cystitis Association at 1–800–435–7422 or www.ichelp.org, and the American Urological Association Foundation at 1–866–746–4282 or www.afud.org.

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Interstitial Cystitis and Painful Bladder Syndrome. IN: Litwin, M.S.; Saigal, C.S., eds. Urologic Diseases in America. Bethesda, MD: National Kidney and Urologic Diseases Information Clearinghouse. pp. 123-156.

Interstitial cystitis (IC) and painful bladder syndrome (PBS) are chronic conditions characterized by frequent urination and bladder pain. Onset frequently occurs in the patient’s fourth decade or after and the disease typically fluctuates in severity but rarely resolves completely. This chapter on IC and PBS is from a lengthy text that offers a comprehensive portrait of the illness burden and resource use associated with the major urologic diseases in the United States. In this chapter, the authors discuss definition and diagnosis, manifestations of disease, prevalence and incidence, risk factors, clinical evaluation, trends in health care resource utilization for this condition, specifically inpatient and outpatient care, and economic impact. They conclude by noting that because no objective marker exists for IC or PBS, the exact prevalence of the disorder is not currently known. Outpatient visits related to these conditions are increasing, perhaps due to an increased awareness of the disorders or to a national increase in the number of patients. A final section offers recommendations in the areas of diagnosis, treatment, and areas of needed research. 4 figures. 26 tables. 18 references.

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Symptoms of Interstitial Cystitis, Painful Bladder Syndrome and Similar Diseases in Women: A Systematic Review. Journal of Urology. 177(2): 450-456. February 2007.

The symptoms of interstitial cystitis (IC) in women can be difficult to differentiate from those of painful bladder syndrome and may also overlap with symptoms of urinary tract infection (UTI), chronic urethral syndrome, overactive bladder, vulvodynia, and endometriosis. This article reports the results of a systematic literature review undertaken to determine how best to distinguish IC from related conditions. The authors screened 2,680 article titles, of which 604 were read in full. The most commonly reported IC symptoms were bladder or pelvic pain, urgency, frequency, and nocturia. IC and painful bladder syndrome share the same cluster of symptoms. Chronic urethral syndrome is an outdated term. Recurrent UTIs may be differentiated from IC and painful bladder syndrome via a combination of self-report and urine culture information. Pain distinguishes IC from overactive bladder and vulvar pain may distinguish vulvodynia from IC. The authors conclude that identifying IC and painful bladder syndrome in women with more than one of these diseases may be difficult. 4 tables. 68 references.

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What I Need to Know About Interstitial Cystitis/Painful Bladder Syndrome. Bethesda, MD: National Kidney and Urologic Diseases Information Clearinghouse. 2007. 18 p.

This booklet describes interstitial cystitis (IC), a condition that results in recurring discomfort or pain in the bladder and the surrounding pelvic region. Symptoms may include an urgent need to urinate, a frequent need to urinate, or a combination of these symptoms. In recent years, scientists have started to use the term painful bladder syndrome (PBS) to describe cases with painful urinary symptoms that may not meet the strictest definition of IC. Written in a question-and-answer format and using nontechnical language, the fact sheet covers a definition of these urinary conditions; the causes of IC; diagnostic strategies, including urine testing, culture of prostate secretions, cystoscopy under anesthesia with bladder distention, and biopsy; and treatments for IC and PBS, including bladder stretching, bladder medicines, oral drugs, transcutaneous electrical nerve stimulations, diet, smoking cessation, exercise, bladder retraining, physical therapy, oral medications, and surgery. The fact sheet briefly summarizes research programs in this area, provides a list of resource organizations for readers wanting additional information, and briefly describes the activities of the National Kidney and Urologic Diseases Information Clearinghouse. 7 figures. 3 references.

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Drugs Used in the Treatment of Interstitial Cystitis. IN: Eardley, I., et al, eds. Drug Treatment in Urology. Williston, VT: Blackwell Publishing Inc. 2006. pp. 62-73.

Interstitial cystitis (IC) is a chronic, debilitating condition that is characterized by urinary frequency and urgency, together with chronic pelvic or perineal pain. This chapter on drugs used in the treatment of IC is from a book that offers a comprehensive summary of the role of pharmacology in urology. After an introductory section that reviews the epidemiology of IC and the impact of this condition on the patient’s quality of life, the authors summarize the principles of therapy for this difficult-to-manage problem. Therapies can be undertaken for urothelial protection, mast cell or histamine release inhibition, immunogenic response modulation, modulation of neurogenic inflammation, and modulation of nociception. Specific drugs discussed including those approved for the treatment of IC: pentosan polysulphate (Elmiron), hyaluronic acid/sodium hyaluronate (Cystistat), and dimethyl sulphoxide (DMSO or RIMSO-50). The author also reviews some of the research into agents that are not yet licensed for treating IC: hydroxyzein, cimetidine, amitriptyline, L-arginine, bacillus Calmette-Guerin, cyclosporin, heparin, misoprostol, and montelukast; a final section briefly considers future developments in this area, including the use of suplatast tosilate, vanilloid receptor antagonists, resiniferatoxin, botulinum toxin, and gene therapy. 1 table. 45 references.

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Evaluation and Treatment. Female Patient. 31(3): 8-9. March 2006.

This article reviews the evaluation and treatment of painful bladder syndrome (PBS), also known as interstitial cystitis (IC). The author begins by emphasizing that this condition can be challenging to treat and diagnose; it has no known cause and no specific diagnostic test to identify it. Most patients are female and usually have the following three symptoms: bladder pain, discomfort or pressure; urinary frequency; and urinary urgency. Readers are encouraged to be as specific as possible when describing their symptoms to the health care provider; suggestions for organizing one’s thoughts before a doctor’s appointment are provided. The author also lists questions that patients can answer before they meet with their health care provider; this preparation may result in a more satisfactory interview process and a quicker, more accurate diagnosis.

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Focus on Pelvic Pain in Men (and Women): NIDDK Conference Brings New Perspectives on Pelvic Pain. ICA Update. p. 7-9. January- February 2006.

This newsletter article reports on a recent conference (October 2005, Baltimore, Maryland), the Chronic Pelvic Pain-Chronic Prostatitis Scientific Workshop, which was sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). Although a major focus was on chronic prostatitis in men, the conference also discussed interstitial cystitis (IC). The article outlines some of the workshop sessions, which covered neuropathic pain, pelvic pain conditions that occur in tandem with other pain conditions, how the pelvic organs are innervated and how pain from them is transmitted, pudendal neuralgia, the use of nerve blocks, new drugs that are currently in research studies, the role of inflammation in pelvic pain, the use of opioids to treat chronic pelvic pain, the genetic origins of pain sensitivity and responses, the differences in gender reactions to pain and to analgesic therapy, new approaches to measuring pain, working in tandem with patients to design measurements that are valuable to the patients as well as to the researchers, and the integration of physical and psychological therapies. The author notes the workshop presenters’ names and affiliations, although contact information is not provided.

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Interstitial Cystitis and Chronic Pelvic Pain. IN: Kellogg Parsons, J.; James Wright, E., eds. Brady Urology Manual. New York, NY: Informa Healthcare USA. 2006. pp 85-94.

This chapter about interstitial cystitis (IC)/chronic pelvic pain is from a reference handbook that offers a comprehensive overview of urology, presented in outline and bulleted formats for ease of access in the busy health care world of hospital emergency rooms and outpatient clinics. The author notes that IC/chronic pelvic pain syndrome is a chronic, often unrecognized, lower urinary tract disease. The chapter covers epidemiology, pathophysiology, presentation, symptoms, diagnostic strategies, medical therapy, and surgical therapy. Primary symptoms of IC include one or more of the following: urinary frequency, urinary urgency, and pelvic pain. Other symptoms can include nocturia, dysuria, dyspareunia, and testicular, scrotal, and perineal pain. IC may be caused by bladder epithelial dysfunction, which leads to diffusion of urinary solutes, notably potassium, into the bladder interstitium, tissue injury, and inappropriate afferent nerve stimulation. Patient evaluation should include history with validated symptom questionnaire, physical examination, urinalysis, and urine culture. Additional tests that might be used include the potassium sensitivity test, cystoscopy, and urodynamics. The author concludes that urinary diversion should be considered only in patients with severe disease that is refractory to less invasive therapies. The chapter concludes with a list of references for additional reading. 2 figures. 54 references.

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Intestinal Cystitis - Painful Bladder Syndrome Checklist. Female Patient. 31(3): 14. March 2006.

This single-page article provides a checklist that readers can use as they cope with the problem of painful bladder syndrome (PBS), also known as interstitial cystitis (IC). The author stresses that evaluation and treatment of bladder pain progresses step by step. The checklist provides a list of what to expect at each of six visits to a health care provider. The first visit includes diagnostic questions, a physical examination, laboratory tests, and a discussion of test results. The second visit includes more detailed tests, a discussion about management of PBS and IC, and planning for treatment, including dietary therapy, physical therapy, and medications (a list of common medications used is provided). The third and following visits are for progress review and have fewer items on their checklist. Readers are reminded that health care providers may differ in the specific approach to PBS and IC, but this checklist gives an overview of what to expect.

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