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Your search term(s) "Diagnostic Tests" returned 58 results.
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Multiple Myeloma. IN: Sekeres, M.; Kalaycio, M.; Bolwell, B., eds. Clinical Malignant Hematology. Columbus, OH: McGraw Hill. 2007. pp 833-936.
This section about multiple myeloma is from a comprehensive reference book that covers the full spectrum of cancers in the blood, bone marrow, and lymphatic system, including leukemia, lymphoma, and myeloma. Multiple myeloma (MM) is characterized by the proliferation of malignant plasma cells in the bone marrow, bone destruction, extramedullary plasmacytoma, renal failure, and, late in the disease course, marrow failure manifested as anemia, leukopenia, and thrombocytopenia. This section offers eight chapters: the epidemiology of and risk factors for MM, including incidence and etiology; molecular biology, pathology, and cytogenetics; clinical features and making the diagnosis; the initial treatment approach to MM; treatment strategies; allogeneic stem cell transplantation for MM; a definition of remission, and issues of prognosis and follow-up; and treatment of relapsed or refractory MM and new frontiers in MM therapy. The chapters are illustrated with black-and-white clinical pictures and photomicrographs, and each chapter concludes with an extensive list of references.
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Myelodysplastic Syndromes. IN: Sekeres, M.; Kalaycio, M.; Bolwell, B., eds. Clinical Malignant Hematology. Columbus, OH: McGraw Hill. 2007. pp 367-444.
This section about myelodysplastic syndromes (MDS) is from a comprehensive reference book that covers the full spectrum of cancers in the blood, bone marrow, and lymphatic system, including leukemia, lymphoma, and myeloma. The myelodysplastic syndrome is a heterogeneous group of clonal neoplastic stem cell disorders and is characterized by bone marrow failure with peripheral cytopenias and a tendency to progress to acute myeloid leukemia (AML). This section offers seven chapters: molecular biology, pathology, and cytogenetics in MDS; clinical features and making the diagnosis; the recommended treatment approach for early MDS; aplastic anemia and stem cell failure; allogeneic stem cell transplantation for MDS and aplastic anemia; definition of remission, prognosis, and follow-up in patients with MDS; and treatment of relapsed or refractory MDS and new frontiers in MDS therapy. The chapters are illustrated with black-and-white clinical pictures and photomicrographs. Each chapter concludes with an extensive list of references.
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Non-Hodgkin’s Lymphoma. IN: Sekeres, M.; Kalaycio, M.; Bolwell, B., eds. Clinical Malignant Hematology. Columbus, OH: McGraw Hill. 2007. pp 503-722.
This section about non-Hodgkin’s lymphoma (NHL) is from a comprehensive reference book that covers the full spectrum of cancers in the blood, bone marrow, and lymphatic system, including leukemia, lymphoma, and myeloma. This section offers 18 chapters: the classification of NHL; pathology and molecular genetics of NHL; treatment approach to follicular lymphomas; the treatment approach to diffuse large B-cell lymphomas; the recommended treatment approach to mantle cell lymphoma; the treatment approach to high-grade NHL; the treatment approach to marginal zone and mucosa-associated lymphoid tissue (MALT) lymphomas; the treatment approach to primary central nervous system lymphomas; treatment approach to cutaneous lymphomas; the diagnosis and therapy of mature T-cell NHL; the recommended treatment approach to HIV-related lymphomas; posttransplant lymphoproliferative disorders; the treatment approach to adult T-cell lymphoma or leukemia; the use of autologous hematopoietic cell transplantation for NHL; the use of allogeneic hematopoietic stem cell transplantation for NHL; a definition of remission, prognosis, and follow-up in follicular lymphoma and diffuse large B-cell lymphoma; treatment for transformed NHL; and new frontiers in therapy for NHL. The chapters are illustrated with black-and-white clinical pictures and photomicrographs. Each chapter concludes with an extensive list of references. This section contains the 60 full-color plates for the entire textbook.
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Platelet Disorders. IN: Provan, D., ed. ABC of Clinical Haematology. Williston, VT: Blackwell Publishing Inc. 2007. pp. 33-39.
Platelets, produced from bone marrow megakaryocytes, are important in the formation of platelet plugs during normal hemostasis. This chapter about platelet disorders is from a book on clinical hematology, written by specialists for nonspecialists. The book is designed to be easy to use and covers the symptoms, investigations, treatment, and management of conditions presenting in day-to-day practice. In this chapter, the authors first review normal hemostasis and then discuss congenital abnormalities, including Fanconi’s anemia, thrombocytopenia with absent radii (TAR syndrome), Wiskott-Aldrich syndrome, MYH9-related thrombocytopenias, disorders of the surface membrane, and platelet storage pool diseases; acquired abnormalities, including decreased production of platelets, increased consumption of platelets, idiopathic thrombocytopenic purpura, post-transfusion purpura, neonatal alloimmune thrombocytopenia, heparin-induced thrombocytopenia, thrombotic thrombocytopenic purpura, microangiopathic thrombocytopenia, disseminated intravascular coagulation, massive blood transfusion, massive splenomegaly, drug-induced platelet disorders, bleeding in patients with uremia, and thrombocytosis; diagnostic tests used to confirm a suspected platelet disorder; and the management of congenital and acquired disorders. The chapter is illustrated with full-color photographs, drawings, and charts. 9 figures. 5 tables. 7 references.
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Reproductive Issues. Montreal, Quebec: Canadian Hemophilia Society. 2007. pp 57-78.
This chapter on reproductive issues is from a monograph that provides information for female carriers of hemophilia A and B, a type of genetic bleeding disorder traditionally experienced by males but passed on genetically by females. Recent understanding of this disorder shows that females can have the same problems as males with mild hemophilia, such as hemorrhaging after surgery or trauma. Women with clotting factor levels as high as 60 percent can have abnormal bleeding problems, including but not restricted to gynecological and obstetrical bleeding. This chapter deals with many questions related to reproduction, including family planning, conception options, challenges to conception, prenatal diagnosis of hemophilia, miscarriages, pregnancy, labor and delivery, postpartum care, breastfeeding, care for the newborn with hemophilia, hysterectomy, and perimenopausal bleeding. Prenatal diagnostic options discussed include ultrasound, chorionic villus sampling (CVS), amniocentesis, fetal blood sampling, and maternal blood tests currently under development. Readers are encouraged to educate themselves about the heredity of hemophilia and the options available for reproduction and prenatal diagnosis. 1 table.
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Sarcoidosis. New England Journal of Medicine. 357(21): 2153-2165. November 2007.
This article brings readers up to date on the research regarding sarcoidosis and addresses potential pitfalls in the diagnosis and management of this condition. The authors review epidemiology, the search for environmental causes, genetic features, immunopathogenesis, clinical features, diagnostic tests used to confirm the condition, pulmonary involvement, cutaneous involvement, liver and spleen involvement, neurologic involvement, ophthalmologic complications, cardiac sarcoidosis, hypercalcemia and renal disease, bone and joint involvement, sarcoidosis in children, drug therapy, and the use of transplantation. Although sarcoidal granulomas can involve any organ, in more than 90 percent of people with the condition, clinical sarcoidosis is manifested as intrathoracic lymph-node enlargement, pulmonary involvement, skin or ocular signs and symptoms, or some combination of these findings. Most people are not disabled by the illness, so the decision to provide treatment with corticosteroids, the most common therapy, must be considered in light of the risks and benefits of those drugs. 3 figures. 3 tables. 95 references.
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Special Topics in Leukemia. IN: Sekeres, M.; Kalaycio, M.; Bolwell, B., eds. Clinical Malignant Hematology. Columbus, OH: McGraw Hill. 2007. pp 311-366.
This section about special topics in leukemia is from a comprehensive reference book that covers the full spectrum of cancers in the blood, bone marrow, and lymphatic system, including leukemia, lymphoma, and myeloma. This section offers four chapters: the management of fever and neutropenia in leukemia; autologous stem cell transplantation for leukemia; allogeneic hematopoietic stem cell transplantation for acute leukemias in adults; and transplantation in chronic leukemia. The first chapter reviews basic principles of the physical examination, laboratory studies, and radiography and clinical syndromes associated with the management of fever and neutropenia in patients with leukemia. The authors provide updates on the spectrum of infecting organisms, antimicrobial resistance, newer antimicrobial agents, and innovative strategies such as outpatient and home intravenous therapy. The authors of the second and fourth chapters maintain that allogeneic transplant remains the only proven cure for chronic myelogenous leukemia (CML) and should be strongly considered in young, highly motivated patients with HLA-identical siblings. The chapters are illustrated with black-and-white clinical pictures and photomicrographs. Each chapter concludes with an extensive list of references.
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Special Topics in Lymphoma. IN: Sekeres, M.; Kalaycio, M.; Bolwell, B., eds. Clinical Malignant Hematology. Columbus, OH: McGraw Hill. 2007. pp 815-832.
This brief section about special topics in lymphoma is from a comprehensive reference book that covers the full spectrum of cancers in the blood, bone marrow, and lymphatic system, including leukemia, lymphoma, and myeloma. This section offers two chapters: the epidemiology of second malignancies following lymphoma therapy and screening recommendations, and the appropriate use of positron emission tomography (PET) and gallium scans in lymphoma. The authors of the first chapter note that much of the excess mortality in lymphoma survivors is from second malignancies, which are now recognized as a direct consequence of curative chemotherapy and radiation therapy. The recently recognized importance of these often-fatal late effects of treatment has focused efforts in both screening and prevention. The author of the second chapter notes that both gallium scintigraphy and PET have shown advantages in defining active lymphoma over classical imaging alone. The greater technical ease and apparent improved accuracy of PET imaging are contributing to its increasing acceptance as the functional imaging modality of choice in the care of lymphoma patients. The chapters are illustrated with black-and-white clinical pictures and photomicrographs. Each chapter concludes with an extensive list of references.
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Special Topics in Multiple Myeloma. IN: Sekeres, M.; Kalaycio, M.; Bolwell, B., eds. Clinical Malignant Hematology. Columbus, OH: McGraw Hill. 2007. pp 937-974.
This section about special topics in multiple myeloma is from a comprehensive reference book that covers the full spectrum of cancers in the blood, bone marrow, and lymphatic system, including leukemia, lymphoma, and myeloma. Multiple myeloma (MM) is characterized by the proliferation of malignant plasma cells in the bone marrow, bone destruction, extramedullary plasmacytoma, renal failure, and, late in the disease course, marrow failure manifested as anemia, leukopenia, and thrombocytopenia. This section offers four chapters: hyperviscosity syndrome; monoclonal gammopathy of undetermined significance; amyloidosis; and treatment of complications in multiple myeloma. The chapters are illustrated with black-and-white clinical pictures and photomicrographs. Each chapter concludes with an extensive list of references.
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Special Topics in Neoplastic Hematology. IN: Sekeres, M.; Kalaycio, M.; Bolwell, B., eds. Clinical Malignant Hematology. Columbus, OH: McGraw Hill. 2007. pp 1089-1190.
This section about special topics in neoplastic hematology is the concluding section in a comprehensive reference book that covers the full spectrum of cancers in the blood, bone marrow, and lymphatic system, including leukemia, lymphoma, and myeloma. This section offers nine chapters: the pharmacology of traditional agents used to treat hematologic malignancies; the biological response of modifying agents in the treatment of hematologic malignancies; the pharmacology of monoclonal antibodies; blood product transfusions in the hematologic malignancies; growth factor support in the hematologic malignancies; the recommended treatment approach to pregnant women; tumor lysis syndrome, disseminated intravascular coagulopathy, and other noninfectious complications of leukemia and lymphoma; fertility issues in the hematologic malignancies; and the palliation of symptoms associated with hematologic malignancies. The chapters are illustrated with black-and-white clinical pictures and photomicrographs. Each chapter concludes with an extensive list of references.
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