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Sponsored by: |
Merck |
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Information provided by: | Merck |
ClinicalTrials.gov Identifier: | NCT00092209 |
The purpose of this study is to evaluate antihypertensive (lowering blood pressure) effectiveness of three combinations of approved study drugs compared to both study drugs being given alone.
Condition | Intervention | Phase |
---|---|---|
Hypertension |
Drug: MK0954A, hydrochlorothiazide (+) losartan potassium Drug: Comparator: placebo, losartan, hydrochorothiazide |
Phase III |
Study Type: | Interventional |
Study Design: | Treatment, Randomized, Double-Blind, Active Control, Parallel Assignment, Efficacy Study |
Official Title: | A Randomized, Placebo-Controlled, Double-Blind, Parallel Study of the Anti-Hypertensive Efficacy and Safety of Losartan Monotherapy as Compared to HCTZ Monotherapy and to the Combination of Losartan and HCTZ in Japanese Patients With Essential Hypertension |
Ages Eligible for Study: | 25 Years to 74 Years |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
Exclusion Criteria:
Responsible Party: | Merck & Co., Inc. ( Executive Vice President, Clinical and Quantitative Sciences ) |
Study ID Numbers: | 2004_065 |
Study First Received: | September 21, 2004 |
Last Updated: | January 2, 2008 |
ClinicalTrials.gov Identifier: | NCT00092209 |
Health Authority: | United States: Food and Drug Administration |
Losartan Vascular Diseases Essential hypertension |
Angiotensin II Hydrochlorothiazide Hypertension |
Molecular Mechanisms of Pharmacological Action Diuretics Physiological Effects of Drugs Sodium Chloride Symporter Inhibitors Cardiovascular Agents Antihypertensive Agents Pharmacologic Actions |
Membrane Transport Modulators Angiotensin II Type 1 Receptor Blockers Natriuretic Agents Therapeutic Uses Cardiovascular Diseases Anti-Arrhythmia Agents |