Male and female patients at least 18 years of age and diagnosed with type 2 diabetes mellitus treated in an ambulatory care setting and who are taking metformin, a sulfonylurea, or a combination of metformin and sulfonylurea, but have not achieved adequate glycemic control. Female patients eligible of becoming pregnant are required to have some form of contraception while participating in the study.

Inclusion Criteria:

• are male or female outpatients at least 18 years of age
• provide written consent to the release of their data after being informed of the study
• diagnosed with type 2 diabetes mellitus and are taking metformin, or a sulfonylurea or both
• are reliable, and agree to keep all appointments for clinic visits, complete tests and procedures as may be required by the attending physician in the course of routine clinical care
• are treated with exenatide according to the approved Product Insert, as prescribed by the investigator in the routine care of the patient

Exclusion Criteria:

• are simultaneously participating in a different study that includes a treatment intervention and/or an investigational drug.
• are currently taking insulin.
• are pregnant or have intentions of becoming pregnant within the duration of the study.
• are the investigators or their immediate families. Immediate family is defined as the investigator's spouse, parents, natural or legally adopted child (including stepchild living in the investigator's household), grandparents, or grandchild. Employees of investigators are also not eligible.