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Sponsored by: |
AstraZeneca |
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Information provided by: | AstraZeneca |
ClinicalTrials.gov Identifier: | NCT00620178 |
This study is a Swedish historical cohort study in patients prescribed Atacand or Cozaar for hypertension by selected primary care centres. Data will be extracted anonymously from electronic medical records. In addition, data regarding morbidity and mortality will be collected by merging the cohort with the following national registries: the Hospital Discharge Register (Slutenvårdsregistret), the Cause of Death Register and the Heart Intensive Care Admission (RIKS-HIA)
Condition | Intervention |
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Hypertension |
Drug: Candesartan Cilexetil Drug: Losartan |
Study Type: | Observational |
Study Design: | Cohort, Retrospective |
Official Title: | A REtrospective Study on the Effects of cAndesartan vs. Losartan on Blood Pressure, Health Care Consumption and cardiovascuLar Events In a "Real-liFe" GP sEtting in Sweden |
Estimated Enrollment: | 14000 |
Study Start Date: | February 2008 |
Study Completion Date: | August 2008 |
Primary Completion Date: | May 2008 (Final data collection date for primary outcome measure) |
Groups/Cohorts | Assigned Interventions |
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1
Candesartan
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Drug: Candesartan Cilexetil
oral once daily dose
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2
Losartan
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Drug: Losartan
once daily oral dose
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Ages Eligible for Study: | 17 Years and older |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Sampling Method: | Non-Probability Sample |
Eligible subjects are all patients found in EPS systems at the participating centres, who were prescribed candesartan (ATC-C09CA06) or losartan (C09CA01) for hypertension from 1 January 1999 - 31 December 2004 inclusive. The first found prescription is designated as index.
Inclusion Criteria:
Exclusion Criteria:
Responsible Party: | AstraZeneca ( Anders Ljunggren, MD ) |
Study ID Numbers: | NIS-CSE-ATA-2008/1 |
Study First Received: | February 8, 2008 |
Last Updated: | September 8, 2008 |
ClinicalTrials.gov Identifier: | NCT00620178 |
Health Authority: | Sweden: Regional Ethical Review Board |
candesartan losartan blood pressure cardiovascular disease health care consumption |
Candesartan cilexetil Losartan Candesartan |
Vascular Diseases Angiotensin II Hypertension |
Angiotensin II Type 1 Receptor Blockers Molecular Mechanisms of Pharmacological Action Therapeutic Uses Cardiovascular Diseases |
Cardiovascular Agents Anti-Arrhythmia Agents Antihypertensive Agents Pharmacologic Actions |