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Sponsors and Collaborators: |
University of Southern Denmark Bristol-Myers Squibb |
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Information provided by: | University of Southern Denmark |
ClinicalTrials.gov Identifier: | NCT00125645 |
The purpose of this study is to compare changes in global left ventricular (LV) function after 3 months of treatment with irbesartan compared with usual care in patients with acute myocardial infarction, a wall motion score >1.3 (EF>0.40) and signs of diastolic dysfunction. The hypothesis is that an angiotensin 2-receptor inhibitor will improve global left ventricular function.
Condition | Intervention | Phase |
---|---|---|
Myocardial Infarction |
Drug: Irbesartan |
Phase IV |
Study Type: | Interventional |
Study Design: | Treatment, Randomized, Open Label, Uncontrolled, Parallel Assignment, Efficacy Study |
Official Title: | Global Left Ventricular Function After Acute Myocardial Infarction. Treatment With the Angiotensin 2-Receptor Blocker Irbesartan |
Estimated Enrollment: | 200 |
Study Start Date: | March 2005 |
Estimated Study Completion Date: | July 2008 |
Ages Eligible for Study: | 18 Years and older |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
Exclusion Criteria:
Contact: Allan T Pedersen, MD | +4523368158 | Thimsen@dadlnet.dk |
Contact: Kristian K Thomsen, MD | +4579182210 | kkt@ribeamt.dk |
Denmark | |
Kardiologisk Klinik, Centralsygehuset Esbjerg/Varde | Recruiting |
Esbjerg, Denmark, 6700 | |
Contact: Allan T Pedersen, MD +4523368158 Thimsen@dadlnet.dk | |
Principal Investigator: Allan T Pedersen, MD |
Study Chair: | Kenneth Egstrup, Asst. Professor | Department of Medical Research, SHF Svendborg |
Study ID Numbers: | VF 20040053, 2612 |
Study First Received: | July 29, 2005 |
Last Updated: | April 24, 2007 |
ClinicalTrials.gov Identifier: | NCT00125645 |
Health Authority: | Denmark: Danish Medicines Agency |
AMI Left ventricular function Myocardial performance index Acute myocardial infarction (AMI) |
Necrosis Heart Diseases Myocardial Ischemia Irbesartan Vascular Diseases |
Ischemia Angiotensin II Infarction Myocardial Infarction |
Angiotensin II Type 1 Receptor Blockers Pathologic Processes Molecular Mechanisms of Pharmacological Action Therapeutic Uses |
Cardiovascular Diseases Cardiovascular Agents Antihypertensive Agents Pharmacologic Actions |